ArticleNature2022
Intracellular lipid surveillance by small G protein geranylgeranylation.
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Article in Nature, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
4.0field-weighted citation impact, top 6% of its field
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
23 citing papers in PubMed, 31 citations in OpenAlex.
- Article
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- Free long-chain fatty acids trigger early postembryonic development in starved Caenorhabditis elegans by suppressing mTORC1.PLoS biology · 2024Article
- A framework for intestinal barrier dysfunction in aging.Nature aging · 2023Article
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- Endosomal trafficking protein TBC-2 is required for the longevity of long-lived mitochondrial mutants.Frontiers in aging · 2023Article
- Nuclear hormone receptor NHR-49 is an essential regulator of stress resilience and healthy aging inFrontiers in physiology · 2023Review
- Intracellular lipid surveillance: Modulating protein dynamics through lipid sensing.Clinical and translational medicine · 2022Article
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Authors and funding
13 authors at 3 institutions in 1 country.
Abigail WattersonDepartment of Molecular Biology, University of Texas Southwestern Medical Center, Dallas, TX, USA.ORCID http://orcid.org/0000-0002-5204-0907
Lexus TatgeDepartment of Molecular Biology, University of Texas Southwestern Medical Center, Dallas, TX, USA.ORCID http://orcid.org/0000-0003-4211-7808
Naureen WajahatDepartment of Molecular Biology, University of Texas Southwestern Medical Center, Dallas, TX, USA.ORCID http://orcid.org/0000-0001-6623-7893
Sonja L B ArneaudDepartment of Molecular Biology, University of Texas Southwestern Medical Center, Dallas, TX, USA.ORCID http://orcid.org/0000-0002-1123-3876
Rene Solano FonsecaDepartment of Molecular Biology, University of Texas Southwestern Medical Center, Dallas, TX, USA.ORCID http://orcid.org/0000-0002-5927-5936
Shaghayegh T BeheshtiDepartment of Molecular Biology, University of Texas Southwestern Medical Center, Dallas, TX, USA.
Patrick MetangDepartment of Molecular Biology, University of Texas Southwestern Medical Center, Dallas, TX, USA.
Melina MihelakisDepartment of Molecular Biology, University of Texas Southwestern Medical Center, Dallas, TX, USA.ORCID http://orcid.org/0000-0003-3357-9090
Kielen R ZuurbierDepartment of Molecular Biology, University of Texas Southwestern Medical Center, Dallas, TX, USA.ORCID http://orcid.org/0000-0002-8979-9829
Chase D CorleyCenter for Human Nutrition, University of Texas Southwestern Medical Center, Dallas, TX, USA.
Ishmael DehghanDepartment of Molecular Biology, University of Texas Southwestern Medical Center, Dallas, TX, USA.
Jeffrey G McDonaldCenter for Human Nutrition, University of Texas Southwestern Medical Center, Dallas, TX, USA.ORCID http://orcid.org/0000-0003-1570-4142
Peter M DouglasDepartment of Molecular Biology, University of Texas Southwestern Medical Center, Dallas, TX, USA. peter.douglas@utsouthwestern.edu.ORCID http://orcid.org/0000-0002-0734-1049
The University of Texas Southwestern Medical Center · USThe University of Texas at Dallas · USSouthwestern Medical Center · US
Funding
Lipid sensing through G protein geranylgeranylationR01AG076529 · NIA · UT SOUTHWESTERN MEDICAL CENTER · PI Peter Mahan Douglas · 2022 to 2026
$1.7MHeat Shock Factor mediates actin phosphorylation in tissue integrity and ageR01AG061338 · NIA · UT SOUTHWESTERN MEDICAL CENTER · PI DOUGLAS, PETER MAHAN · 2019 to 2023
$1.7MCell Non-Autonomous nature of the Heat Shock ResponseR00AG042495 · NIA · UT SOUTHWESTERN MEDICAL CENTER · PI DOUGLAS, PETER MAHAN · 2015 to 2017
$728kLipid sensing through small G protein prenylationR56AG070167 · NIA · UT SOUTHWESTERN MEDICAL CENTER · PI DOUGLAS, PETER MAHAN · 2021 to 2021
$336kNIA NIH HHS R00 AG042495NIA NIH HHS R01 AG061338NIA NIH HHS R01 AG076529NIA NIH HHS R56 AG070167
Abstract
Imbalances in lipid homeostasis can have deleterious effects on health
Indexed as
Caenorhabditis elegans ProteinsMonomeric GTP-Binding ProteinsAnimalsCaenorhabditis elegansLipidsProtein PrenylationReceptors, Cytoplasmic and NuclearCaenorhabditis elegans ProteinsLipidsMonomeric GTP-Binding ProteinsReceptors, Cytoplasmic and Nuclear
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.