Evidence map›Paper›PMID 35584875›Full record

ArticleBMJ open2022

Sex differences and rehabilitation needs after hospital discharge for COVID-19: an Italian cross-sectional study.

Stefania Fugazzaro, Monica Denti, Carlotta Mainini, Monia Allisen Accogli, Ginevra Bedogni, Daniele Ghizzoni, Anna Bertolini, Otmen Esseroukh, Cecilia Gualdi, Margherita Schiavi and 2 more

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in BMJ open, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04438239 (Rehabilitation Needs After COVID-19 Hospital Treatment), which is not on this map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.1field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04438239 completednot on this map

Rehabilitation Needs After COVID-19 Hospital Treatment (REACT): an Observational Study

TypeobservationalSponsorAzienda USL Reggio Emilia - IRCCSRan2020 to 2020Enrolled150ConditionsCovid-19Armsnone, this study is observational
3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Activities Carried Out during the First COVID-19 Lockdown by Italian Citizens.International journal of environmental research and public health · 2023
    Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Stefania FugazzaroPhysical Medicine and Rehabilitation Unit, Azienda Unità Sanitaria Locale - IRCCS Tecnologie Avanzate e Modelli Assistenziali in Oncologia di Reggio Emilia, Reggio Emilia, Italy.
Monica DentiPhysical Medicine and Rehabilitation Unit, Azienda USL - IRCCS di Reggio Emilia, Reggio Emilia, Italy monica.denti@ausl.re.it.ORCID 0000-0001-6541-2696
Carlotta MaininiPhysical Medicine and Rehabilitation Unit, Azienda Unità Sanitaria Locale - IRCCS Tecnologie Avanzate e Modelli Assistenziali in Oncologia di Reggio Emilia, Reggio Emilia, Italy.
Monia Allisen AccogliPhysical Medicine and Rehabilitation Unit, Azienda Unità Sanitaria Locale - IRCCS Tecnologie Avanzate e Modelli Assistenziali in Oncologia di Reggio Emilia, Reggio Emilia, Italy.
Ginevra BedogniPhysical Medicine and Rehabilitation Unit, Azienda Unità Sanitaria Locale - IRCCS Tecnologie Avanzate e Modelli Assistenziali in Oncologia di Reggio Emilia, Reggio Emilia, Italy.
Daniele GhizzoniPhysiotherapy Service, Private Hospital Villa Verde Srl, Reggio Emilia, Italy.
Anna BertoliniDepartment of Medical and Sugical Sciences;University of Modena e Reggio, Bachelor' degree in OT, Modena e Reggio Emilia, Italy.
Otmen EsseroukhDepartment of Surgery, Medicine, DentristY and Morphological Sciences; University of Modena e Reggio Emilia, Bachelor's degree PT, Modena e Reggio Emilia, Italy.
Cecilia GualdiDepartment of Surgery, Medicine, DentristY and Morphological Sciences; University of Modena e Reggio Emilia, Bachelor's degree PT, Modena e Reggio Emilia, Italy.
Margherita SchiaviDepartment of Health Professions, Azienda USL - IRCCS di Reggio Emilia, Reggio Emilia, Italy.ORCID 0000-0002-3154-5658
Luca BragliaResearch and Statistic Infrastructure, Azienda USL - IRCCS di Reggio Emilia, Reggio Emilia, Italy.
Stefania CostiDepartment of Medical and Sugical Sciences;University of Modena e Reggio, Bachelor' degree in OT, Modena e Reggio Emilia, Italy.ORCID 0000-0002-4645-0336
Tecnologie Avanzate (Italy) · ITUniversity of Modena and Reggio Emilia · ITAzienda Sanitaria Unità Locale di Reggio Emilia · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesCOVID-19 can result in persistent symptoms leaving potential rehabilitation needs unmet. This study aims to describe persistent symptoms and health status of individuals hospitalised for COVID-19 according to the International Classification of Functioning, Disability and Health domains of impairments, limitations in activity, and participation restrictions.

designCross-sectional study consisting in a telephone interview 3 months after hospital discharge.

settingThis study was conducted during the first peak of the COVID-19 pandemic by the Local Health Authority of Reggio Emilia (Italy).

participantsAdult individuals discharged from hospital between April and June 2020 after COVID-19. EXCLUSION CRITERIA: hospitalisation for reasons other than COVID-19, inability to participate in the study, concomitant acute or chronic conditions causing disability. PRIMARY AND SECONDARY OUTCOME MEASURES: We assessed: dyspnoea (Medical Research Council), fatigue (Fatigue Severity Scale), mood disturbances (Hospital Anxiety and Depression Scale), limitations in activity (Barthel Index) and participation restrictions (Reintegration to Normal Living Index). We also collected data on sociodemographic characteristics, health status prior to COVID-19, COVID-related clinical manifestations and hospital care pathway up to discharge, rehabilitation interventions, accidental falls and emergency room access.

results149 participants (men, 62%; average age 62 (±11) years) were enrolled, 35 of which (23%) were admitted to the intensive care unit (ICU) while hospitalised. Three months after hospital discharge, nearly half of the participants still suffered from dyspnoea (44%) or fatigue (39%). Almost all individuals (91.2%) recovered a good level of independence in activity of daily living, but 76% still suffered participation restrictions. Female sex was significantly associated with worse outcomes for all symptoms.

conclusionsIndividuals who had moderate or severe COVID-19 may perceive persistent symptoms which may result in reduced social participation. Sex differences should be monitored, as women may recover more slowly than men. TRIAL REGISTRATION NUMBER: NCT04438239.

Indexed as

COVID-19AdultCross-Sectional StudiesDyspneaFatigueFemaleHospitalsHumansMaleMiddle AgedPandemicsPatient DischargeSex CharacteristicsTreatment OutcomeCOVID-19rehabilitation medicinerespiratory infections

Identifiers

PMID35584875
PMCPMC9118361
OpenAlexW4280532985

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.