ArticleCurrent biology : CB2022
Isolation disrupts social interactions and destabilizes brain development in bumblebees.
Article in Current biology : CB, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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13 citing papers in PubMed.
- Cyclic thermal stress during pupation triggers irreversible carry-over effects in a key pollinator.Communications biology · 2026Article
- Extended amygdala orchestrates social motivation in socially isolated mice.bioRxiv : the preprint server for biology · 2026Article
- Independent and joint associations of depressive symptoms and social isolation on trajectories of functional disability among middle-aged and older adults.Archives of public health = Archives belges de sante publique · 2026Article
- Absence of pesticide avoidance during chronic colony-level exposure modifies locomotor activity in bumble bees.Ecotoxicology (London, England) · 2026Article
- Early social isolation disrupts adult personality expression in group-living mites.The Journal of animal ecology · 2025Article
- Integrating computer vision and molecular neurobiology to bridge the gap between behavior and the brain.Current opinion in insect science · 2024Review
- No sensitive period for the development of individual face learning inBehavioral ecology and sociobiology · 2024Article
- Fantastic beasts and how to study them: rethinking experimental animal behavior.The Journal of experimental biology · 2024Article
- NAPS: Integrating pose estimation and tag-based tracking.Methods in ecology and evolution · 2023Article
- Non-uniform temporal scaling of developmental processes in the mammalian cortex.Nature communications · 2023Article
- Postural analysis reveals persistent changes in paper wasp foundress behavioral state after conspecific challenge.Ecology and evolution · 2023Article
- Putting hornets on the genomic map.Scientific reports · 2023Article
- Affective Neuroscience of Loneliness: Potential Mechanisms underlying the Association between Perceived Social Isolation, Health, and Well-Being.Journal of psychiatry and brain science · 2022Article
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Abstract
Social isolation, particularly in early life, leads to deleterious physiological and behavioral outcomes. Here, we leverage new high-throughput tools to comprehensively investigate the impact of isolation in the bumblebee, Bombus impatiens, from behavioral, molecular, and neuroanatomical perspectives. We reared newly emerged bumblebees in complete isolation, in small groups, or in their natal colony, and then analyzed their behaviors while alone or paired with another bee. We find that when alone, individuals of each rearing condition show distinct behavioral signatures. When paired with a conspecific, bees reared in small groups or in the natal colony express similar behavioral profiles. Isolated bees, however, showed increased social interactions. To identify the neurobiological correlates of these differences, we quantified brain gene expression and measured the volumes of key brain regions for a subset of individuals from each rearing condition. Overall, we find that isolation increases social interactions and disrupts gene expression and brain development. Limited social experience in small groups is sufficient to preserve typical patterns of brain development and social behavior.
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