ArticleAmerican journal of respiratory and critical care medicine2022
Muscle Protein Synthesis after Protein Administration in Critical Illness.
Article in American journal of respiratory and critical care medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
52 citing papers in PubMed, 5 syntheses or guidelines pooled it, 127 citations in OpenAlex.
- Effects of higher versus lower protein intake in critically ill patients: a systematic review and meta-analysis.Frontiers in nutrition · 2026Pooled it
- The intensive care medicine research agenda for the management of ICU acquired weakness: a multinational, interprofessional perspective.Intensive care medicine · 2025Pooled it
- The urea-to-creatinine ratio as an emerging biomarker in critical care: a scoping review and meta-analysis.Critical care (London, England) · 2025Pooled it
- The effects of higher versus lower protein delivery in critically ill patients: an updated systematic review and meta-analysis of randomized controlled trials with trial sequential analysis.Critical care (London, England) · 2024Pooled it
- A systematic review and meta-analysis of the clinimetric properties of the core outcome measurement instruments for clinical effectiveness trials of nutritional and metabolic interventions in critical illness (CONCISE).Critical care (London, England) · 2023Pooled it
- Low versus standard calorie and protein feeding and renal dysfunction in ventilated adults with shock: a NUTRIREA-3 post hoc analysis.Intensive care medicine · 2026Trial
- The impact of a tailored nutrition intervention delivered for the duration of hospitalisation on daily energy delivery for patients with critical illness (INTENT): a phase II randomised controlled trial.Critical care (London, England) · 2025Trial
- Association between urea trajectory and protein dose in critically ill adults: a secondary exploratory analysis of the effort protein trial (RE-EFFORT).Critical care (London, England) · 2024Trial
- A pilot study of alternative substrates in the critically Ill subject using a ketogenic feed.Nature communications · 2023Trial
- The metabolic effects of intermittent versus continuous feeding in critically ill patients.Scientific reports · 2023Trial
- The impact of higher protein dosing on outcomes in critically ill patients with acute kidney injury: a post hoc analysis of the EFFORT protein trial.Critical care (London, England) · 2023Trial
- Association between age and outcomes of evidence-based feeding protocol versus usual care in critically ill patients: secondary analysis of a multicenter cluster-randomised controlled trial.Journal of intensive care · 2026Article
- Strategies to mitigate muscle mass loss in individuals with spinal cord injury.The journal of spinal cord medicine · 2026Review
- Inflammation Course and Skeletal Muscle Wasting Correlation During the First Week in ICU: A New Approach for Personalised Feeding of Critically Ill Patients?Journal of personalized medicine · 2026Article
- Adenosine 5'-monophosphate prevents sepsis-associated muscle wasting by activating AMPK and suppressing IL-1β inflammatory cytokines.Journal of intensive care · 2026Article
- Muscle catabolism: mechanisms and functional consequences in critically ill patients.Intensive care medicine · 2026Article
- Interpreting protein dose trials in critical illness: a guide for the bedside clinician.Critical care (London, England) · 2026Review
- Current concepts on feeding the critically ill patient: a narrative review.Critical care (London, England) · 2026Review
- The metabolic effects of post-sepsis feeding of meals with only essential amino acids.Clinical science (London, England : 1979) · 2026Article
- Prediction model for quality of life in sepsis survivors one year after discharge.World journal of emergency medicine · 2026Article
Corrections and comments
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Authors and funding
11 authors at 5 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
PubMed holds no abstract for this paper.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.