Evidence map›Paper›PMID 35584325›Full record

ArticleAmerican journal of physiology. Cell physiology2022

Kir7.1 disease mutant T153I within the inner pore affects K

Katie M Beverley, Pawan K Shahi, Meha Kabra, Qianqian Zhao, Joseph Heyrman, Jack Steffen, Bikash R Pattnaik

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in American journal of physiology. Cell physiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.0field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Special collection on inward rectifying KAmerican journal of physiology. Cell physiology · 2023
    Article
  6. Review
  7. Inward rectifier potassium (Kir) channels in the retina: living our vision.American journal of physiology. Cell physiology · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Katie M BeverleyEndocrinology and Reproductive Physiology Graduate Program, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin.
Pawan K ShahiDepartment of Pediatrics, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin.
Meha KabraDepartment of Pediatrics, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin.
Qianqian ZhaoDepartment of Biostatistics and Medical Informatics, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin.
Joseph HeyrmanDepartment of Pediatrics, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin.
Jack SteffenDepartment of Pediatrics, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin.
Bikash R PattnaikEndocrinology and Reproductive Physiology Graduate Program, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin.ORCID 0000-0002-5385-358X
University of Wisconsin–Madison · US

Funding

VIVARIUM MODULEP30EY007003 · NEI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI David Antonetti · 1987 to 2026
$17.6M
UW Vision Research Core - Administrative CoreP30EY016665 · NEI · UNIVERSITY OF WISCONSIN-MADISON · PI ROBERT W NICKELLS · 2005 to 2026
$12.6M
Restoring Vision with High-Fidelity Nonsense Codon CorrectionR24EY032434 · NEI · UNIVERSITY OF WISCONSIN-MADISON · PI AHERN, CHRISTOPHER A, GAMM, DAVID M · 2021 to 2025
$7.8M
Endocrinology-Reproductive Physiology Training GrantT32HD041921 · NICHD · UNIVERSITY OF WISCONSIN-MADISON · PI BIRD, IAN M. · 2004 to 2022
$3.0M
Molecular Therapies for Lebers Congenital Amaurosis Caused by KCNJ13 MutationsR01EY024995 · NEI · UNIVERSITY OF WISCONSIN-MADISON · PI PATTNAIK, BIKASH RANJAN · 2015 to 2018
$1.5M
NEI NIH HHS P30 EY007003NEI NIH HHS P30 EY016665NEI NIH HHS R01 EY024995NEI NIH HHS R24 EY032434NICHD NIH HHS T32 HD041921
6 · The paper itself

Abstract

Inward-rectifier potassium channel 7.1 (Kir7.1) is present in the polarized epithelium, including the retinal pigmented epithelium. A single amino acid change at position 153 in the

Indexed as

Potassium Channels, Inwardly RectifyingAmino AcidsCell MembraneMembrane PotentialsPatch-Clamp TechniquesAmino AcidsPotassium Channels, Inwardly Rectifyingelectrophysiologyinnerpore structureKir7.1pediatric blindnesspotassium channels

Identifiers

PMID35584325
PMCPMC9273268
OpenAlexW4280503853

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.