Evidence map›Paper›PMID 35584126›Full record

ArticlePloS one2022

STEAM-DWI as a robust alternative to EPI-DWI: Evaluation in pediatric brain MRI.

Daniel Gräfe, Anne Päts, Andreas Merkenschlager, Christian Roth, Franz Wolfgang Hirsch, Jens Frahm, Dirk Voit

Abstract read
In one paragraph

Article in PloS one, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Daniel GräfeDepartment of Pediatric Radiology, Leipzig University, Leipzig, Germany.ORCID 0000-0002-7680-0990
Anne PätsDepartment of Pediatric Radiology, Leipzig University, Leipzig, Germany.
Andreas MerkenschlagerDepartment of Pediatrics, Leipzig University, Leipzig, Germany.
Christian RothDepartment of Pediatric Radiology, Leipzig University, Leipzig, Germany.
Franz Wolfgang HirschDepartment of Pediatric Radiology, Leipzig University, Leipzig, Germany.
Jens FrahmBiomedical NMR, Max Planck Institute for Multidisciplinary Sciences, Göttingen, Germany.
Dirk VoitBiomedical NMR, Max Planck Institute for Multidisciplinary Sciences, Göttingen, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeDiffusion-weighted imaging (DWI) is an essential element of almost every brain MRI examination. The most widely applied DWI technique, a single-shot echo-planar imaging DWI (EPI-DWI) sequence, suffers from a high sensitivity to magnetic field inhomogeneities. As an alternative, a single-shot stimulated echo acquisition mode diffusion-weighted MRI (STEAM-DWI) has recently been re-introduced after it became significantly faster. The aim of the study was to investigate the applicability of STEAM-DWI as a substitute to EPI-DWI in a daily routine of pediatric radiology.

methodsRetrospectively, brain MRI examinations of 208 children with both EPI-DWI and STEAM-DWI were assessed. Visual resolution and diagnostic confidence were evaluated, the extent of susceptibility artifacts was quantified, and contrast-to-noise ratio was calculated in case of diffusion restriction. Furthermore, the correlation of apparent diffusion coefficient values between STEAM-DWI and EPI-DWI was tested.

resultsSTEAM-DWI was inferior to EPI-DWI in visual resolution but with higher diagnostic confidence and lower artifact size. The apparent diffusion coefficient values of both sequences demonstrated excellent correlation. The contrast-to-noise ratio of STEAM-DWI was only half of that of EPI-DWI (58% resp. 112%).

conclusionSTEAM-DWI is a robust alternative to EPI-DWI when increased susceptibility artifacts are to be expected. Drawbacks are a lower contrast-to-noise ratio and poorer visual resolution.

Indexed as

Diffusion Magnetic Resonance ImagingEcho-Planar ImagingArtifactsBrainChildHumansMagnetic Resonance ImagingReproducibility of ResultsRetrospective Studies

Identifiers

PMID35584126
PMCPMC9116624

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.