Evidence map›Paper›PMID 35583841›Full record

ArticleNeurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology2022

Neural underpinnings of the slowness of information processing in patients with traumatic brain injury: insights from tract-based spatial statistics.

Maddalena Boccia, Sonia Barbetti, Federica Valentini, Carmela De Angelis, Antonio Tanzilli, Valentina Fabio, Cecilia Guariglia, Gaspare Galati, Rita Formisano, Maria Paola Ciurli

Abstract read
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In one paragraph

Article in Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Traumatic brain injuries: a neuropsychological review.Frontiers in behavioral neuroscience · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Maddalena BocciaDepartment of Psychology, "Sapienza" University of Rome, Via dei Marsi, 78, 00185, Rome, Italy. maddalena.boccia@uniroma1.it.ORCID http://orcid.org/0000-0002-2044-8326
Sonia BarbettiDepartment of Human Neuroscience, "Sapienza" University of Rome, Rome, Italy.
Federica ValentiniCentre of Cognitive Neuropsychology, ASST Grande Ospedale Metropolitano, Niguarda Hospital, Milan, Italy.
Carmela De AngelisDepartment of Psychology, "Sapienza" University of Rome, Via dei Marsi, 78, 00185, Rome, Italy.
Antonio TanzilliNeuro-Oncology Unit, I.R.C.C.S. Regina Elena National Cancer Institute, Rome, Italy.
Valentina FabioDepartment of Mental Health and Pathological Addictions, UOC TSMREE, ASL Roma 5, Rome, Italy.
Cecilia GuarigliaDepartment of Psychology, "Sapienza" University of Rome, Via dei Marsi, 78, 00185, Rome, Italy.
Gaspare GalatiDepartment of Psychology, "Sapienza" University of Rome, Via dei Marsi, 78, 00185, Rome, Italy.
Rita FormisanoSanta Lucia Foundation, Rome, Italy.
Maria Paola CiurliNeuropsychology Unit, Santa Lucia Foundation IRCCS Fondazione Santa Lucia, Rome, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Slowness of information processing (SIP) is frequently reported after traumatic brain injury (TBI). Previous studies point toward a pivotal role of white matter damage on speed of information processing. However, little is known about the more comprehensive and ecological assessment of SIP in TBI. Here, we combined an ecological assessment of SIP with the use of tract-based spatial statistics (TBSS) on individuals' fractional anisotropy (FA) maps. Twenty-six moderate-to-severe patients with TBI (21 males and 5 females) participated in this study: 10 individuals were classified as not having SIP (SIP-) and 16 were classified as having SIP (SIP +). SIP + showed lower FA in bilateral anterior thalamic radiation, corticospinal tract, cingulum, and forceps, as well as in bilateral inferior fronto-occipital, inferior and superior longitudinal fasciculi and uncinate fasciculus. Overall, this result is consistent with and expands previous reports on information processing speed to a more comprehensive and ecological perspective on SIP in TBI.

Indexed as

Brain Injuries, TraumaticWhite MatterAnisotropyBrainDiffusion Tensor ImagingFemaleHumansMaleDiffuse axonal injuryDTIMental slownessMRITBITBSS

Identifiers

PMID35583841

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.