Evidence map›Paper›PMID 35583823›Full record

ArticleAbdominal radiology (New York)2022

Physically implausible signals as a quantitative quality assessment metric in prostate diffusion-weighted MR imaging.

Teodora Szasz, Grace Lee, Aritrick Chatterjee, Milica Medved, Ajit Devaraj, Ambereen Yousuf, Xiaobing Fan, Gregory S Karczmar, Aytekin Oto

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In one paragraph

Article in Abdominal radiology (New York), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 4 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Teodora SzaszResearch Computing Center, The University of Chicago, Chicago, IL, USA. tszasz@uchicago.edu.ORCID 0000-0001-8176-6726
Grace LeeDepartment of Radiology, The University of Chicago, Chicago, IL, USA.
Aritrick ChatterjeeDepartment of Radiology, The University of Chicago, Chicago, IL, USA.ORCID 0000-0003-4022-7106
Milica MedvedDepartment of Radiology, The University of Chicago, Chicago, IL, USA.ORCID 0000-0003-2945-5511
Ajit DevarajPhilips Research North America, Cambridge, USA.
Ambereen YousufDepartment of Radiology, The University of Chicago, Chicago, IL, USA.ORCID 0000-0002-0475-9087
Xiaobing FanDepartment of Radiology, The University of Chicago, Chicago, IL, USA.
Gregory S KarczmarDepartment of Radiology, The University of Chicago, Chicago, IL, USA.ORCID 0000-0002-2455-5858
Aytekin OtoDepartment of Radiology, The University of Chicago, Chicago, IL, USA.ORCID 0000-0003-4325-2489
University of Chicago · USPhilips (United States) · US

Funding

VIRAL ONCOLOGY CORE FACILITYP30CA014599 · NCI · UNIVERSITY OF CHICAGO · PI MARK W. LINGEN · 1985 to 2026
$122.1M
3T MRI Scanner for multidisciplinary imaging and image-guided therapyS10OD018448 · OD · UNIVERSITY OF CHICAGO · PI KARCZMAR, GREGORY S. · 2014 to 2014
$2.0M
MR Virtual Pathology of the ProstateR41CA244056 · NCI · QMIS, LLC · PI KARCZMAR, GREGORY S., MUSTAFI, DEVKUMAR · 2020 to 2020
$225k
NCI NIH HHS P30 CA014599NCI NIH HHS R41 CA244056NIH HHS R01 CA17280NIH HHS R01 CA227036NIH HHS S10 OD018448
6 · The paper itself

Abstract

purposeTo provide a quantitative assessment of diffusion-weighted MR images of the prostate through identification of PIDS which clearly represents artifacts in the data. We calculated the percentage and distribution of PIDS in prostate DWI and compare the amount of PIDS between mpMRI images obtained with and without an endorectal coil.

methodsThis IRB approved retrospective study (from 03/03/2014 to 03/10/2020), included 40 patients scanned with endorectal coil (ERC) and 40 without ER coil (NERC). PIDS contains any voxel where: (1) the diffusion signal increases despite an increase in b-value; and/or (2) apparent diffusion coefficient (ADC) is more than 3.0 μm

results80 patients (58 ± 8 years old, 80 men) were evaluated. The percentage of voxels exhibiting PIDS was 17.1 ± 8.1% for the ERC cohort and 22.2 ± 15.5% for the NERC cohort. PIDS for NERC versus ERC were not significantly different (p = 0.14). The apex and base showed similar percentages of PIDS in ERC (p = 0.30) and NERC (p = 0.86). The mid (13.8 ± 8.6%) in ERC showed lower values (p = 0.02) of PIDS compared to apex (19.9 ± 11.1%) and base (17.5 ± 8.3%).

conclusionPIDS maps provide a spatially resolved quantitative quality assessment for prostate DWI. Average PIDS over the entire prostate were similar for the ERC and NERC cohorts, and did not differ significantly across prostate zones. However, for many of the patients, PIDS was focally much higher in specific prostate zones. PIDS assessment can guide Radiologist's evaluation of images and the development of improved DWI sequences.

Indexed as

ProstateProstatic NeoplasmsAgedDiffusion Magnetic Resonance ImagingHumansMagnetic Resonance ImagingMaleMiddle AgedRetrospective StudiesDiffusion-weighted MRIMultiparametric MRIProstate DWIQuality assessmentQuantitative measurement

Identifiers

PMID35583823
OpenAlexW4280498213

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.