Evidence map›Paper›PMID 35583693›Full record

ArticleAnnals of surgical oncology2022

Surgical and Oncologic Outcomes of Robotic and Conventional Nipple-Sparing Mastectomy with Immediate Reconstruction: International Multicenter Pooled Data Analysis.

Hyung Seok Park, Jeea Lee, Hung-Wen Lai, Jung Mi Park, Jai Min Ryu, Jeong Eon Lee, Jee Ye Kim, Emilia Marrazzo, Alessandra Margherita De Scalzi, Giovanni Corso and 4 more

Registry-linked trialOpen access · greenAbstract readMulticenter Study
PubMed Publisher
In one paragraph

Article in Annals of surgical oncology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04108117 (Surgical and Oncologic Outcomes After Robotic Nipple Sparing Mastectomy and Immediate Reconstruction), which is not on this map. Cited by 46 papers, 10 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed, 10 pooled it
12.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04108117 completednot on this map

Surgical and Oncologic Outcomes After Robotic Nipple Sparing Mastectomy and Immediate Reconstruction : an International Multicenter Pooled Analysis

TypeobservationalSponsorSeverance HospitalRan2020 to 2022Enrolled659ConditionsPostoperative Complications, Recurrence, Breast Neoplasms, Breast CancerArmsRobotic nipple sparing mastectomy
3 · Its place in the literature

Who cites it

46 citing papers in PubMed, 10 syntheses or guidelines pooled it, 60 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 8 institutions in 3 countries.

Hyung Seok Park *Department of Surgery, Yonsei University College of Medicine, Seoul, Korea.
Jeea Lee *Department of Surgery, Uijeongbu Eulji Medical Center, Eulji University, Uijeongbu, Gyeonggi-do, Korea.
Hung-Wen LaiEndoscopic and Oncoplastic Breast Surgery Center, Changhua Christian Hospital, Changhua, Taiwan.
Jung Mi ParkDepartment of Biostatistics and Computing, Graduate School, Yonsei University, Seoul, Korea.
Jai Min RyuBreast Division, Department of Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
Jeong Eon LeeBreast Division, Department of Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
Jee Ye KimDepartment of Surgery, Yonsei University College of Medicine, Seoul, Korea.
Emilia MarrazzoBreast Unit, Department of Surgery, Ospedale Maggiore di Lodi, ASST di Lodi, Lodi, Italy.
Alessandra Margherita De ScalziDivision of Breast Surgery, School of Medicine, European Institute of Oncology IRCCS, University of Milan, Milan, Italy.
Giovanni CorsoDivision of Breast Surgery, School of Medicine, European Institute of Oncology IRCCS, University of Milan, Milan, Italy.
Filippo MontemurroBreast Surgery Strategic Program, Candiolo Cancer Institute, FPO - IRCCS, Str. Provinciale 142, Candiolo, Torino, Italy.
Guglielmo GazzettaBreast Surgery Strategic Program, Candiolo Cancer Institute, FPO - IRCCS, Str. Provinciale 142, Candiolo, Torino, Italy.
Giada PozziBreast Surgery Strategic Program, Candiolo Cancer Institute, FPO - IRCCS, Str. Provinciale 142, Candiolo, Torino, Italy.
Antonio ToescaBreast Surgery Strategic Program, Candiolo Cancer Institute, FPO - IRCCS, Str. Provinciale 142, Candiolo, Torino, Italy. antonio.toesca@libero.it.
Candiolo Cancer Institute · ITYonsei University · KRSamsung Medical Center · KRChanghua Christian Hospital · TWEulji University · KREuropean Institute of Oncology · ITFondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico · ITUniversity of Milan · IT

Funding

Clinical Robotic Research Grant 5558241
6 · The paper itself

Abstract

backgroundRobotic nipple-sparing mastectomy (RNSM) has been developed to reduce conspicuous scar and increase the quality of life in women. This study aimed to evaluate the surgical and oncologic outcomes of RNSM with immediate breast reconstruction (IBR) compared with conventional nipple-sparing mastectomy (CNSM). PATIENTS AND

methodsThis international multicenter, pooled analysis of individual patient-level data enrolled a total of 755 procedures in 659 women (609 had breast cancer and 50 underwent risk-reducing mastectomy) who underwent nipple-sparing mastectomy with IBR. Surgical and oncologic outcomes, including 30-days postoperative (POD 30d) complication rate, nipple necrosis rate, grade of Clavien-Dindo classification, disease-free survival, and overall survival, were evaluated. Propensity score-matched analyses were performed to adjust for confounding factors.

resultsThe median age of both the RNSM and CNSM groups was 45 years. The RNSM group had lower body mass index (BMI) and a higher proportion of benign disease compared with the CNSM group. POD 30d complications and postoperative complication grade III rates were lower in the RNSM group than in the CNSM group (p < 0.05). The nipple necrosis rate was 2.2% and 7.8% for RNSM and CNSM, respectively (p = 0.002). After propensity score matching, significantly lower rates of POD 30d complications, nipple necrosis, and postoperative complication grade III occurred in the RNSM group than in the CNSM group (all p < 0.05). Oncologic outcomes were not significantly different between the two groups.

conclusionRNSM can provide better cosmetic results with favorable surgical and oncologic outcomes for women with early breast cancer or BRCA mutation.

Indexed as

Breast NeoplasmsMammaplastyRobotic Surgical ProceduresData AnalysisFemaleHumansMastectomyMiddle AgedNecrosisNipplesPostoperative ComplicationsQuality of LifeRetrospective Studies

Identifiers

PMID35583693
OpenAlexW4280578995

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.