Evidence map›Paper›PMID 35583582›Full record

ReviewChinese journal of integrative medicine2024

Molecular Mechanism of Polysaccharides Extracted from Chinese Medicine Targeting Gut Microbiota for Promoting Health.

Wen-Xiao Zhao, Tong Wang, Ya-Nan Zhang, Qian Chen, Yuan Wang, Yan-Qing Xing, Jun Zheng, Chen-Chen Duan, Li-Jun Chen, Hai-Jun Zhao and 1 more

Abstract readReview
PubMed Publisher
In one paragraph

Review in Chinese journal of integrative medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 20 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Review
  6. Article
  7. Review
  8. Review
  9. Frontiers in nutrition · 2025
    Review
  10. Article
  11. Frontiers in pharmacology · 2024
    Article
  12. Modulating effects ofJournal of Zhejiang University. Science. B · 2023
    Article
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Wen-Xiao ZhaoSchool of Nursing, Shandong University of Traditional Chinese Medicine, Shandong University of Traditional Chinese Medicine, Ji'nan, 250355, China.
Tong WangSchool of Nursing, Shandong University of Traditional Chinese Medicine, Shandong University of Traditional Chinese Medicine, Ji'nan, 250355, China.
Ya-Nan ZhangShandong Co-innovation Center of Classic Traditional Chinese Medicine Formula, Shandong University of Traditional Chinese Medicine, Ji'nan, 250355, China.
Qian ChenShandong Co-innovation Center of Classic Traditional Chinese Medicine Formula, Shandong University of Traditional Chinese Medicine, Ji'nan, 250355, China.
Yuan WangShandong Co-innovation Center of Classic Traditional Chinese Medicine Formula, Shandong University of Traditional Chinese Medicine, Ji'nan, 250355, China.
Yan-Qing XingSchool of Nursing, Shandong University of Traditional Chinese Medicine, Shandong University of Traditional Chinese Medicine, Ji'nan, 250355, China.
Jun ZhengSchool of Nursing, Shandong University of Traditional Chinese Medicine, Shandong University of Traditional Chinese Medicine, Ji'nan, 250355, China.
Chen-Chen DuanSchool of Nursing, Shandong University of Traditional Chinese Medicine, Shandong University of Traditional Chinese Medicine, Ji'nan, 250355, China.
Li-Jun ChenSchool of Nursing, Shandong University of Traditional Chinese Medicine, Shandong University of Traditional Chinese Medicine, Ji'nan, 250355, China.
Hai-Jun ZhaoShandong Co-innovation Center of Classic Traditional Chinese Medicine Formula, Shandong University of Traditional Chinese Medicine, Ji'nan, 250355, China. higherzhao@126.com.
Shi-Jun WangShandong Co-innovation Center of Classic Traditional Chinese Medicine Formula, Shandong University of Traditional Chinese Medicine, Ji'nan, 250355, China.
Shandong University of Traditional Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The accumulating evidence revealed that gut microbiota plays an important role in pathological process of disease including obesity, type 2 diabetes mellitus, heart failure, and non-alcoholic fatty liver disease. Polysaccharides extracted from Chinese medicine (CM) can not only alleviate pathological status but also promote health by anti-inflammatory, regulating immunity, lowering blood glucose and lipids, anti-cancer, and anti-oxidation. The alterations of gut microbiota composition and metabolism pathways are the potential mechanisms of CM polysaccharides treatment. In addition, they exert functions through gut-organ axis or play an indirect role by synergistic actions with other drugs or components mediated by gut microbiota. This review summarizes the molecular mechanisms of CM polysaccharides interacted with intestinal microbial inhabitants as potential prebiotics for promoting health.

Indexed as

Diabetes Mellitus, Type 2Gastrointestinal MicrobiomeHealth PromotionHumansMedicine, Chinese TraditionalPolysaccharidesPrebioticsPolysaccharidesPrebioticsChinese medicinegut microbiotagut-organ axislipopolysaccharidespolysaccharidesshort-chain fatty acidssynergistic actions

Identifiers

PMID35583582
OpenAlexW4280595542

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.