Evidence map›Paper›PMID 35583526›Full record

ArticleMedicine2022

Comparison of efficacy and safety of traditional Chinese patent medicines for diabetic nephropathy: A protocol for Bayesian network meta-analysis.

Shilin Liu, Andong Li, Bin Jiang, Jia Mi, Hongmei Nan, Pengjie Bao, Zheng Nan

Open access · goldAbstract read
In one paragraph

Article in Medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 54% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Shilin LiuChangchun University of Chinese Medicine, 1035 Bo Shuo Road, Changchun City, Jilin Province, China.
Andong LiChangchun University of Chinese Medicine, 1035 Bo Shuo Road, Changchun City, Jilin Province, China.
Bin JiangChangchun University of Chinese Medicine, 1035 Bo Shuo Road, Changchun City, Jilin Province, China.
Jia MiChangchun University of Chinese Medicine, 1035 Bo Shuo Road, Changchun City, Jilin Province, China.
Hongmei NanChangchun University of Chinese Medicine, 1035 Bo Shuo Road, Changchun City, Jilin Province, China.
Pengjie BaoChangchun University of Chinese Medicine, 1035 Bo Shuo Road, Changchun City, Jilin Province, China.
Zheng NanChangchun University of Chinese Medicine, 1035 Bo Shuo Road, Changchun City, Jilin Province, China.ORCID 0000-0002-0616-7472
Changchun University of Chinese Medicine · CNWeatherford College · US

Funding

the National Key Research and Development Program 2018YFC1704102
6 · The paper itself

Abstract

backgroundDiabetic nephropathy (DN) is one of the most serious complications of diabetes. It has become a global public health problem among humans. DN is the leading cause of end-stage renal disease. At present, there is no specific medicine or modern medicinal therapy. In recent years, studies have shown that traditional Chinese patent medicines have been effective in treating DN, with few side effects. There is no systematic review on the treatment of DN with Chinese patent medicines. The current systematic review aims to evaluate the efficacy and safety of Chinese patent medicines for the treatment of DN.

methodsWe will develop a search strategy to search major Chinese and English databases from inception to February 25, 2022 for randomized controlled trials examining the use of traditional Chinese patent medicine for the treatment of DN. The search will be conducted in accordance with the participants, interventions, comparisons, outcomes (PICOS) framework. Two researchers will use EndnoteX9 software to extract data and independently evaluate the quality of the included trials. Finally, the Bayesian network meta-analysis will be carried out by using software such as ReviewManager, Stata16.0, and WinBUGS1.4.3.

resultsThe primary outcomes will be urine albumin excretion rate, urea nitrogen, serum creatinine, total effective rate, and adverse events, and the secondary outcomes will be body mass index, fasting blood glucose, and 2-hPG during 75-g OGTT. These outcomes will be examined to provide a reliable basis for the treatment of DN with different traditional Chinese patent medicines.

conclusionThis review will compare the efficacy and safety of different traditional Chinese patent medicines for treating DN. The results of the study will provide a basis for the selection of adjuvant treatment options for DN.

Indexed as

Diabetes MellitusDiabetic NephropathiesDrugs, Chinese HerbalBayes TheoremChinaHumansMedicine, Chinese TraditionalNetwork Meta-Analysis as TopicNonprescription DrugsReview Literature as TopicDrugs, Chinese HerbalNonprescription Drugs

Identifiers

PMID35583526
PMCPMC9276373
OpenAlexW4280562907

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.