Evidence map›Paper›PMID 35583518›Full record

ArticleNano letters2022

ROS-Targeted Depression Therapy via BSA-Incubated Ceria Nanoclusters.

Shengyang Fu, Huili Chen, Weitao Yang, Xiaohuan Xia, Shu Zhao, Xiaonan Xu, Pu Ai, Qingyuan Cai, Xiangyu Li, Yi Wang and 3 more

Open access · bronzeAbstract read
In one paragraph

Article in Nano letters, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed, 1 pooled it
6.2field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 1 synthesis or guideline pooled it, 88 citations in OpenAlex.

  1. Pooled it
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  17. Enhancing Antioxidant and Cytotoxic Properties of CeONanomaterials (Basel, Switzerland) · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 2 countries.

Shengyang FuCenter for Translational Neurodegeneration and Regenerative Therapy, Tongji Hospital affiliated to Tongji University School of Medicine, Shanghai 200065, China.
Huili ChenCenter for Translational Neurodegeneration and Regenerative Therapy, Tongji Hospital affiliated to Tongji University School of Medicine, Shanghai 200065, China.
Weitao YangThe Institute for Translational Nanomedicine, Shanghai East Hospital, Shanghai 200120, China.
Xiaohuan XiaCenter for Translational Neurodegeneration and Regenerative Therapy, Tongji Hospital affiliated to Tongji University School of Medicine, Shanghai 200065, China.
Shu ZhaoCenter for Translational Neurodegeneration and Regenerative Therapy, Tongji Hospital affiliated to Tongji University School of Medicine, Shanghai 200065, China.
Xiaonan XuCenter for Translational Neurodegeneration and Regenerative Therapy, Tongji Hospital affiliated to Tongji University School of Medicine, Shanghai 200065, China.
Pu AiCenter for Translational Neurodegeneration and Regenerative Therapy, Tongji Hospital affiliated to Tongji University School of Medicine, Shanghai 200065, China.
Qingyuan CaiCenter for Translational Neurodegeneration and Regenerative Therapy, Tongji Hospital affiliated to Tongji University School of Medicine, Shanghai 200065, China.
Xiangyu LiCenter for Translational Neurodegeneration and Regenerative Therapy, Tongji Hospital affiliated to Tongji University School of Medicine, Shanghai 200065, China.
Yi WangCenter for Translational Neurodegeneration and Regenerative Therapy, Yangzhi Rehabilitation Hospital affiliated to Tongji University, Shanghai 200065, China.
Jie ZhuCenter for Translational Neurodegeneration and Regenerative Therapy, Shanghai Tenth People's Hospital affiliated to Tongji University School of Medicine, Shanghai 200065, China.
Bingbo ZhangThe Institute for Translational Nanomedicine, Shanghai East Hospital, Shanghai 200120, China.ORCID 0000-0002-0981-7071
Jialin C ZhengCenter for Translational Neurodegeneration and Regenerative Therapy, Tongji Hospital affiliated to Tongji University School of Medicine, Shanghai 200065, China.ORCID 0000-0003-2286-0151
Tongji University · CNShanghai Sunshine Rehabilitation Center · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Depression is one of the most fatal mental diseases, and there is currently a lack of efficient drugs for the treatment of depression. Emerging evidence has indicated oxidative stress as a key pathological feature of depression. We targeted reactive oxygen species (ROS) and synthesized CeO

Indexed as

NanostructuresSerum Albumin, BovineDepressionOxidative StressReactive Oxygen SpeciesReactive Oxygen SpeciesSerum Albumin, Bovinebovine serum albuminCeriadepressionreactive oxygen species

Identifiers

PMID35583518
PMCPMC9185743
OpenAlexW4280541409

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.