Integrated Approach to Interaction Studies of Pyrene Derivatives with Bovine Serum Albumin: Insights from Theory and Experiment.

Selvaraj Sengottiyan, Kakoli Malakar, Arunkumar Kathiravan, Marappan Velusamy, Alicja Mikolajczyk, Tomasz Puzyn

Open access · hybridAbstract read

In one paragraph

Article in The journal of physical chemistry. B, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it

0cells of the map it votes in

2citing papers in PubMed

0.6field-weighted citation impact, top 36% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 7 citations in OpenAlex.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Selvaraj SengottiyanLaboratory of Environmental Chemoinformatics, Faculty of Chemistry, University of Gdansk, Wita Stwosza 63, Gdansk, 80-308 Poland.ORCID 0000-0003-1264-6901

Kakoli MalakarDepartment of Chemistry, North Eastern Hill University, Shillong 793 022, Meghalaya, India.

Arunkumar KathiravanDepartment of Chemistry, Vel Tech Rangarajan Dr. Sagunthala R & D Institute of Science and Technology, Avadi, Chennai 600 062, Tamil Nadu, India.ORCID 0000-0001-6131-460X

Marappan VelusamyDepartment of Chemistry, North Eastern Hill University, Shillong 793 022, Meghalaya, India.ORCID 0000-0001-6488-8000

Alicja MikolajczykLaboratory of Environmental Chemoinformatics, Faculty of Chemistry, University of Gdansk, Wita Stwosza 63, Gdansk, 80-308 Poland.

Tomasz PuzynLaboratory of Environmental Chemoinformatics, Faculty of Chemistry, University of Gdansk, Wita Stwosza 63, Gdansk, 80-308 Poland.ORCID 0000-0003-0449-8339

University of Gdańsk · PLNorth Eastern Hill University · INVel Tech Rangarajan Dr. Sagunthala R&D Institute of Science and Technology · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This work aimed to investigate the interaction of bovine serum albumin with newly synthesized potent new pyrene derivatives (PS1 and PS2), which might prove useful to have a better antibacterial character as found for similar compounds in the previous report [Low et al.

Indexed as

Molecular Dynamics SimulationSerum Albumin, BovineBinding SitesMolecular Docking SimulationProtein BindingPyrenesSpectrometry, FluorescenceThermodynamicsPyrenesSerum Albumin, Bovine

Identifiers

PMID35583491

DOI10.1021/acs.jpcb.2c00778

PMCPMC9169062

OpenAlexW4280492923

What OpenQuestion holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.