Evidence map›Paper›PMID 35583336›Full record

ArticleMicrobiology spectrum2022

Development of an Effective Nontoxigenic Clostridioides difficile-Based Oral Vaccine against C. difficile Infection.

Shaohui Wang, Duolong Zhu, Xingmin Sun

Open access · goldAbstract read
In one paragraph

Article in Microbiology spectrum, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.7field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 18 citations in OpenAlex.

  1. Trial
  2. Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Protection againstbioRxiv : the preprint server for biology · 2024
    Article
  8. International journal of molecular sciences · 2024
    Review
  9. Immunization Strategies Against Clostridioides difficile.Advances in experimental medicine and biology · 2024
    Review
  10. European Practice for CDI Treatment.Advances in experimental medicine and biology · 2024
    Article
  11. Review
  12. Review
  13. Microorganisms · 2023
    Article
  14. Non-ToxigenicAntibiotics (Basel, Switzerland) · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Shaohui WangDepartment of Molecular Medicine, Morsani College of Medicine, University of South Floridagrid.170693.a, Tampa, Florida, USA.
Duolong ZhuDepartment of Molecular Medicine, Morsani College of Medicine, University of South Floridagrid.170693.a, Tampa, Florida, USA.
Xingmin SunDepartment of Molecular Medicine, Morsani College of Medicine, University of South Floridagrid.170693.a, Tampa, Florida, USA.ORCID 0000-0002-8900-9161
University of South Florida · US

Funding

Multivalent vaccines against Clostridium difficile infectionR01AI132711 · NIAID · UNIVERSITY OF SOUTH FLORIDA · PI Xingmin Sun, Shifeng Wang · 2017 to 2026
$3.3M
Novel polymer biomaterials combating C. difficile infectionR01AI149852 · NIAID · UNIVERSITY OF SOUTH FLORIDA · PI CAI, JIANFENG, SUN, XINGMIN · 2019 to 2023
$1.9M
NIAID NIH HHS R01 AI132711NIAID NIH HHS R01 AI149852
6 · The paper itself

Abstract

The symptoms of Clostridioides difficile infection (CDI) are largely attributed to two

Indexed as

Bacterial ToxinsClostridioides difficileClostridium InfectionsAnimalsBacterial ProteinsBacterial VaccinesClostridioidesEnterotoxinsMiceVaccines, SyntheticBacterial ProteinsBacterial ToxinsBacterial VaccinesEnterotoxinsVaccines, Syntheticchimeric proteinClostridioides difficile infectionnontoxigenic Clostridioides difficileoral immunizationsporevaccine

Identifiers

PMID35583336
PMCPMC9241731
OpenAlexW4280513467

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.