ArticleJournal of the American Heart Association2022
Temporal Trends in Adverse Pregnancy Outcomes in Birthing Individuals Aged 15 to 44 Years in the United States, 2007 to 2019.
Article in Journal of the American Heart Association, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
54 citing papers in PubMed, 1 synthesis or guideline pooled it, 63 citations in OpenAlex.
- 2026 AHA/ACC/ADA/ASN Guideline for the Prevention, Detection, Evaluation, and Management of Cardiovascular-Kidney-Metabolic Syndrome: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines.Journal of the American College of Cardiology · 2026Guideline
- Direct Digital Referrals From Prenatal Care and WIC Enrollment Among Pregnant Individuals: A Randomized Clinical Trial.JAMA network open · 2026Trial
- Adverse pregnancy outcomes, longitudinal change in eGFR, and incident hypertension in women: a population-based cohort study.Renal failure · 2026Article
- Hypertensive disorders of pregnancy and women's health throughout the life course: an update review 2025-2026.Hypertension research : official journal of the Japanese Society of Hypertension · 2026Review
- Trends in postpartum hemorrhage, associated risk factors, and severe maternal outcomes in a multihospital health system, 2016-2023: a retrospective cohort study.American journal of obstetrics & gynecology MFM · 2026Article
- Maternal and perinatal outcomes across China's one-child, two-child, and three-child policy periods: a retrospective cohort analysis of 43,439 deliveries.Journal of global health · 2026Article
- Maternal Conditions and Cesarean Delivery in a High-Burden Southeast Louisiana Birth Cohort: Associations and Limitations of Administrative Delivery Data.Healthcare (Basel, Switzerland) · 2026Article
- Paternal Exposure to Endocrine Disrupting Chemicals and Couples' Pregnancy Outcomes: A Qualitative Review of the Literature.Current environmental health reports · 2026Review
- Racial microaggressions in prenatal care settings and perceived quality of prenatal care among Black/African American women.BMC public health · 2026Article
- Observational
- Venture-Backed Maternal Health Startups and the Maternal Health Crisis.JAMA health forum · 2026Article
- Lifetime Adverse Pregnancy Outcome History and Cardiovascular Risk.Hypertension (Dallas, Tex. : 1979) · 2026Article
- Adverse Pregnancy Outcomes and Cardiovascular Health Among Offspring in Early Adulthood.JAMA network open · 2026Article
- Associations between hematologic dynamics during pregnancy and obstetric complications: A retrospective observational study.PLoS medicine · 2026Observational
- Blood Pressure Genetic Risk and Incident Hypertension at 2 to 7 Years Post Partum.JAMA cardiology · 2026Article
- Adverse Pregnancy Outcomes and Long-Term Risk of Chronic Diseases: Evidence from the Findings of the Tehran Lipid and Glucose Study During a Quarter of a Century.International journal of endocrinology and metabolism · 2026Review
- Association Between Changes in Maternal Age Distribution and Hypertensive Disorders of Pregnancy in the United States, 2011-2021.Circulation. Population health and outcomes · 2026Article
- Adverse pregnancy outcomes are associated with cardiovascular and renal dysregulation in late pregnancy.BMC pregnancy and childbirth · 2026Article
- Adverse pregnancy outcomes as predictors of postpartum psychiatric illness: a retrospective cohort study.Archives of women's mental health · 2026Observational
- Yoga as a form of leisure-time physical activity and pregnancy health outcomes.BMC pregnancy and childbirth · 2026Article
Corrections and comments
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Authors and funding
12 authors at 2 institutions in 2 countries.
Funding
Abstract
Background Adverse pregnancy outcomes (APOs) (hypertensive disorders of pregnancy [HDP], preterm delivery [PTD], or low birth weight [LBW]) are associated adverse maternal and offspring cardiovascular outcomes. Therefore, we sought to describe nationwide temporal trends in the burden of each APO (HDP, PTD, LBW) from 2007 to 2019 to inform strategies to optimize maternal and offspring health outcomes. Methods and Results We performed a serial cross-sectional analysis of APO subtypes (HDP, PTD, LBW) from 2007 to 2019. We included maternal data from all live births that occurred in the United States using the National Center for Health Statistics Natality Files. We quantified age-standardized and age-specific rates of APOs per 1000 live births and their respective mean annual percentage change. All analyses were stratified by self-report of maternal race and ethnicity. Among 51 685 525 live births included, 15% were to non-Hispanic Black individuals, 24% Hispanic individuals, and 6% Asian individuals. Between 2007 and 2019, age standardized HDP rates approximately doubled, from 38.4 (38.2-38.6) to 77.8 (77.5-78.1) per 1000 live births. A significant inflection point was observed in 2014, with an acceleration in the rate of increase of HDP from 2007 to 2014 (+4.1% per year [3.6-4.7]) to 2014 to 2019 (+9.1% per year [8.1-10.1]). Rates of PTD and LBW increased significantly when co-occurring in the same pregnancy with HDP. Absolute rates of APOs were higher in non-Hispanic Black individuals and in older age groups. However, similar relative increases were seen across all age,racial and ethnic groups. Conclusions In aggregate, APOs now complicate nearly 1 in 5 live births. Incidence of HDP has increased significantly between 2007 and 2019 and contributed to the reversal of favorable trends in PTD and LBW. Similar patterns were observed in all age groups, suggesting that increasing maternal age at pregnancy does not account for these trends. Black-White disparities persisted throughout the study period.
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Registered trials
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