ArticlemSystems2022
Race, the Vaginal Microbiome, and Spontaneous Preterm Birth.
Article in mSystems, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.
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Who cites it
40 citing papers in PubMed.
- Vaginal Pathogenic Bacterial Colonization and Adverse Birth Outcomes among Pregnant Women Living with and without HIV in Tanzania.Research square · 2026Article
- Longitudinal changes in the vaginal microbiome associate with spontaneous preterm birth: a focus on stability and specific taxa in a Chinese cohort.Microbiology spectrum · 2026Article
- Vaginal microbiome composition in pregnant and non-pregnant women: community structure, population variation, clinical impact, and metagenomics approaches.Infection and immunity · 2026Review
- Vaginal microbiomes and their pertinent social context: a microbial ecological review proffering AMR-STI acquisition and emergence.Biology of sex differences · 2026Review
- The Pathophysiology of Spontaneous Preterm Birth: Emerging Mechanisms Reviewed by the Preterm Birth International Collaborative.Reproductive sciences (Thousand Oaks, Calif.) · 2026Review
- Association of vaginal microbiome, cytokines, and spontaneous preterm birth among Chinese women: a nested case-control study.Microbiology spectrum · 2026Article
- Microflora: a promising potential in the diagnosis and treatment of non-small cell lung cancer.International journal of clinical oncology · 2026Review
- Stool and vaginal microbiome profiles patterns among Black and White endometrial cancer survivors: A pilot study in North Carolina.PloS one · 2026Article
- Vaginal microbiome structure in pregnancy and host factors predict preterm birth: Results from the ECHO Cohort.Annals of epidemiology · 2025Article
- Vaginal microbiome and preterm birth: Composition, mechanisms and microbiota‑directed therapies (Review).International journal of molecular medicine · 2025Review
- Article
- Vaginal microbiome and its implications in preterm birth.Obstetrics & gynecology science · 2025Review
- Article
- Prioritizing precision: guidelines for the better use of population descriptors in human microbiome research.mSystems · 2025Review
- Unveiling the microbial shift: the impact of group B Streptococcus on vaginal microbiota and inflammation in late pregnancy.BMC microbiology · 2025Article
- Increased vaginalmSystems · 2025Article
- Vaginal Microbiome Composition, Diversity and Dysbiosis: The ORCHiD Study.Research square · 2025Article
- Role of age in mediating the association between the vaginal microbiota and preterm birth.mSystems · 2025Article
- Social, microbial, and immune factors linking bacterial vaginosis and infectious diseases.The Journal of clinical investigation · 2025Review
- Compositional transformations can reasonably introduce phenotype-associated values into sparse features.mSystems · 2025Article
Corrections and comments
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Authors and funding
15 authors.
Funding
Abstract
Previous studies have investigated the associations between the vaginal microbiome and preterm birth, with the aim of determining whether differences in community patterns meaningfully alter risk and could therefore be the target of intervention. We report on vaginal microbial analysis of a nested case-control subset of the Pregnancy, Infection, and Nutrition (PIN) Study, including 464 White women (375 term birth and 89 spontaneous preterm birth, sPTB) and 360 Black women (276 term birth and 84 sPTB). We found that the microbiome of Black women has higher alpha-diversity, higher abundance of Lactobacillus iners, and lower abundance of Lactobacillus crispatus. However, among women who douche, there were no significant differences in microbiome by race. The sPTB-associated microbiome exhibited a lower abundance of L. crispatus, while alpha diversity and
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.