Evidence map›Paper›PMID 35582852›Full record

ArticleBiomacromolecules2022

Polymeric Nanotubes as Drug Delivery Vectors─Comparison of Covalently and Supramolecularly Assembled Constructs.

Andrew Kerr, Erny Sagita, Edward D H Mansfield, Tri-Hung Nguyen, Orlagh M Feeney, Colin W Pouton, Christopher J H Porter, Joaquin Sanchis, Sébastien Perrier

Abstract read
In one paragraph

Article in Biomacromolecules, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Principles of Biocompatible Nanotube Design for High-Performance Biomaterials.Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Andrew KerrDepartment of Chemistry, The University of Warwick, Coventry CV4 7AL, U.K.
Erny SagitaDrug Delivery Disposition and Dynamics, Monash Institute of Pharmaceutical Sciences, Monash University, 381 Royal Parade, Parkville 3052, VIC, Australia.
Edward D H MansfieldDepartment of Chemistry, The University of Warwick, Coventry CV4 7AL, U.K.
Tri-Hung NguyenDrug Delivery Disposition and Dynamics, Monash Institute of Pharmaceutical Sciences, Monash University, 381 Royal Parade, Parkville 3052, VIC, Australia.ORCID 0000-0003-4835-2833
Orlagh M FeeneyDrug Delivery Disposition and Dynamics, Monash Institute of Pharmaceutical Sciences, Monash University, 381 Royal Parade, Parkville 3052, VIC, Australia.ORCID 0000-0002-5415-1707
Colin W PoutonDrug Delivery Disposition and Dynamics, Monash Institute of Pharmaceutical Sciences, Monash University, 381 Royal Parade, Parkville 3052, VIC, Australia.ORCID 0000-0003-0224-3308
Christopher J H PorterDrug Delivery Disposition and Dynamics, Monash Institute of Pharmaceutical Sciences, Monash University, 381 Royal Parade, Parkville 3052, VIC, Australia.ORCID 0000-0003-3474-7551
Joaquin SanchisDrug Delivery Disposition and Dynamics, Monash Institute of Pharmaceutical Sciences, Monash University, 381 Royal Parade, Parkville 3052, VIC, Australia.ORCID 0000-0002-7811-8442
Sébastien PerrierDepartment of Chemistry, The University of Warwick, Coventry CV4 7AL, U.K.ORCID 0000-0001-5055-9046

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Rod-shaped nanoparticles have been identified as promising drug delivery candidates. In this report, the in vitro cell uptake and in vivo pharmacokinetic/bio-distribution behavior of molecular bottle-brush (BB) and cyclic peptide self-assembled nanotubes were studied in the size range of 36-41 nm in length. It was found that BB possessed the longest plasma circulation time (

Indexed as

NanoparticlesNanotubesNanotubes, PeptidePeptides, CyclicPolymersNanotubes, PeptidePeptides, CyclicPolymers

Identifiers

PMID35582852
PMCPMC9198979

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.