ArticleWorld journal of gastrointestinal oncology2022
Prognostic significance of serum inflammation indices for different tumor infiltrative pattern types of gastric cancer.
Article in World journal of gastrointestinal oncology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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11 authors.
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Abstract
backgroundInflammatory indices are considered to be potential prognostic biomarkers for patients with gastric cancer (GC). However, there is no evidence defining the prognostic significance of inflammatory indices for GC with different tumor infiltrative pattern (INF) types.
aimTo evaluate the significance of inflammatory indices and INF types in predicting the prognosis of patients with GC.
methodsA total of 962 patients who underwent radical gastrectomy were retrospectively selected for this study. Patients were categorized into the expansive growth type (INFa), the intermediate type (INFb), and the infiltrative growth type (INFc) groups. The cutoff values of inflammatory indices were analyzed by receiver operating characteristic curves. The Kaplan-Meier method and log-rank test were used to analyze overall survival (OS). The chi-square test was used to analyze the association between inflammatory indices and clinical characteristics. The independent risk factors for prognosis in each group were analyzed by univariate and multivariate analyses based on logistic regression. Nomogram models were constructed by R studio.
resultsThe INFc group had the worst OS (
conclusionThe outcome of different INF types GC patients could be assessed by nomograms based on different inflammatory indices and clinicopathologic features.
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