SynthesisWorld journal of gastroenterology2022
Risk of venous thromboembolism in children and adolescents with inflammatory bowel disease: A systematic review and meta-analysis.
Synthesis in World journal of gastroenterology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.
- Pooled it
- Risk factors for early-onset venous thromboembolism in pediatric inflammatory bowel disease.Crohn's & colitis 360 · 2026Article
- Thrombosis and Anemia in Pediatric Inflammatory Bowel Disease: Pathophysiology, Clinical Impact and Future Directions.International journal of molecular sciences · 2025Review
- Thromboprophylaxis in pediatric inflammatory bowel disease: Is it time to reframe the guidelines?Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2025Article
- Prevalence and risk factors of thrombosis in patients with congenital hyperinsulinism: a retrospective analysis.Frontiers in endocrinology · 2025Article
- Multimorbidity disease clusters are associated with venous thromboembolism: an extended cross-sectional national study.Journal of thrombosis and thrombolysis · 2024Article
- Case Report: A case of Crohn's disease with right atrial thrombosis.Frontiers in pediatrics · 2024Article
- Subtypes of Venous Thromboembolism in Inflammatory Bowel Disease: A Nationwide Assessment.Clinical research and clinical trials · 2024Article
- A hypothesis - generating Swedish extended national cross-sectional family study of multimorbidity severity and venous thromboembolism.BMJ open · 2023Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundA two- to three-fold increased risk of venous thrombotic events (VTE) has been demonstrated in patients with inflammatory bowel disease (IBD) compared to the general population, but less is known about the risk of VTE in child- and pediatric-onset IBD. In recent years, several studies have reported the rising incidence rate of VTE in juvenile patients with IBD, and the related risk factors have been explored.
aimTo evaluate the risk of VTE in children and adolescents with IBD.
methodsArticles published up to April 2021 were retrieved from PubMed, Embase, Cochrane Library, Web of Science, SinoMed, CNKI, and WANFANG. Data from observational studies and clinical work were extracted. The outcome was the occurrence of VTE according to the type of IBD. The available odds ratio (OR) and the corresponding 95% confidence interval (CI) were extracted to compare the outcomes. Effect size (P), odds ratio (OR), and 95%CI were used to assess the association between VTE risk and IBD disease. Subgroup analyses stratified by subtypes of VTE and IBD were performed.
resultsTwelve studies (7450272 IBD patients) were included in the meta-analysis. Child and adolescent IBD patients showed increased VTE risk (
conclusionThe current meta-analysis showed that the incidence and risk of VTE are significantly increased in pediatric and adolescent IBD patients. Thus, IBD might be a risk factor for VTE in children and young adults. High-quality prospective cohort studies are necessary to confirm these findings.
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