ArticlePhysiological reports2022
Influence of head-up tile and lower body negative pressure on the internal jugular vein.
Article in Physiological reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 7 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
7 citing papers in PubMed.
- Dose-dependent reduction of optic nerve sheath diameter during graded lower body negative pressure in healthy adults of both sexes.Frontiers in network physiology · 2026Article
- Internal jugular venous flow responses to graded lower body negative pressure: a sex-stratified analysis.Frontiers in physiology · 2026Article
- Integrative cardiovascular dose-response to graded lower-body negative pressure.Experimental physiology · 2025Article
- Impact of patient positioning on bleeding rate in stereotactic brain biopsies: semi-sitting versus supine position.Acta neurochirurgica · 2025Article
- Posture-Induced Changes in Intraocular, Orbital, Cranial, Jugular Vein, and Arterial Pressures in a Porcine Model.Investigative ophthalmology & visual science · 2023Article
- Corrigendum: Influence of head-up tilt and lower body negative pressure on the internal jugular vein.Physiological reports · 2022Article
- Influence of head-up tile and lower body negative pressure on the internal jugular vein.Physiological reports · 2022Article
Corrections and comments
- Erratum issued
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Head-up tilt (HUT)-induced gravitational stress causes collapse of the internal jugular vein (IJV) by decreasing central blood volume and through mass-effect from the surrounding tissues. Besides HUT, lower body negative pressure (LBNP) is used to stimulate orthostatic stress as an experimental model. Compared to HUT, LBNP has less of a gravitational effect because of the supine position; therefore, we hypothesized that LBNP causes less of a decrease in the cross-sectional area of the IJV compared to HUT. We tested the hypothesis by measuring the cross-sectional area of the IJV using B-mode ultrasonography while inducing orthostatic stress at levels of -40 mmHg LBNP and 60° HUT. The cross-sectional area of IJV decreased from the resting baseline during both LBNP and HUT trials, but the LBNP-induced decrease in the cross-sectional area of IJV was smaller than that of HUT (right, -45% ± 49% vs. -78% ± 27%, p = 0.008; left, -49% ± 27% vs. -78% ± 20%, p = 0.004). Since changes in venous outflow may affect cerebral arterial circulation, the findings of the present study suggest that orthostatic stress induced by different techniques modulates cerebral blood flow regulation through its effect on venous outflow.
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