Evidence map›Paper›PMID 35581737›Full record

ArticlePhysiological reports2022

Adults with well-healed burn injuries have lower pulmonary function values decades after injury.

Joseph C Watso, Steven A Romero, Gilbert Moralez, Mu Huang, Matthew N Cramer, Manall F Jaffery, Bryce N Balmain, Daniel P Wilhite, Tony G Babb, Craig G Crandall

Open access · goldAbstract read
In one paragraph

Article in Physiological reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Joseph C WatsoDepartment of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas, USA.ORCID 0000-0001-7840-0643
Steven A RomeroDepartment of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas, USA.ORCID 0000-0002-2014-7806
Gilbert MoralezDepartment of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas, USA.ORCID 0000-0002-0654-2383
Mu HuangDepartment of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas, USA.ORCID 0000-0001-9526-7944
Matthew N CramerDepartment of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas, USA.ORCID 0000-0001-7400-8353
Manall F JafferyDepartment of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Bryce N BalmainDepartment of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas, USA.ORCID 0000-0002-2642-7083
Daniel P WilhiteDepartment of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Tony G BabbDepartment of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Craig G CrandallDepartment of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas, USA.ORCID 0000-0001-7792-9713
Texas Health Dallas · USUniversity of North Texas · US

Funding

Exercise in Burn Survivors - Administrative Supplement for EquipmentR01GM068865 · NIGMS · UT SOUTHWESTERN MEDICAL CENTER · PI CRANDALL, CRAIG G · 2003 to 2023
$7.0M
Heat waves and the elderly: reducing thermal and cardiovascular consequencesR01AG069005 · NIA · UT SOUTHWESTERN MEDICAL CENTER · PI CRANDALL, CRAIG G · 2021 to 2025
$2.8M
Vascular Conditioning in Burn SurvivorsF32GM117693 · NIGMS · UT SOUTHWESTERN MEDICAL CENTER · PI ROMERO, STEVEN A. · 2016 to 2017
$91k
Ketamine-induced Hypertensive Episodes: Adverse Central and Peripheral Neurovascular ActionsF32HL154559 · NHLBI · UT SOUTHWESTERN MEDICAL CENTER · PI WATSO, JOSEPH · 2021 to 2021
$50k
NIGMS NIH HHS F32 GM117693NIGMS NIH HHS R01 GM068865NIH HHS F32HL154559NIH HHS R01AG069005
6 · The paper itself

Abstract

Sub-acute (e.g., inhalation injury) and/or acute insults sustained during a severe burn injury impairs pulmonary function. However, previous work has not fully characterized pulmonary function in adults with well-healed burn injuries decades after an injury. Therefore, we tested the hypothesis that adults with well-healed burn injuries have lower pulmonary function years after recovery. Our cohort of adults with well-healed burn-injuries (n = 41) had a lower forced expiratory volume in one second (Burn: 93 ± 16 vs. Control: 103 ± 10%predicted, mean ± SD; d = 0.60, p = 0.04), lower maximal voluntary ventilation (Burn: 84 [71-97] vs. Control: 105 [94-122] %predicted, median [IQR]; d = 0.84, p < 0.01), and a higher specific airway resistance (Burn: 235 ± 80 vs. Control: 179 ± 40%predicted, mean ± SD; d = 0.66, p = 0.02) than non-burned control participants (n = 12). No variables were meaningfully influenced by having a previous inhalation injury (d ≤ 0.44, p ≥ 0.19; 13 of 41 had an inhalation injury), the size of the body surface area burned (R

Indexed as

BurnsAdultCohort StudiesHumansRespiratory Function Testsbody surface areainhalation injurylung diffusing capacitylung volumesspirometry

Identifiers

PMID35581737
PMCPMC9114657
OpenAlexW4280493962

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.