ArticleLangenbeck's archives of surgery2022
Quantification of gastric tube perfusion following esophagectomy using fluorescence imaging with indocyanine green.
Article in Langenbeck's archives of surgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
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Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.
- The effectiveness of intraoperative indocyanine green fluorescence imaging in preventing anastomotic leakage after minimally invasive esophagectomy for esophageal cancer: a systematic review and meta-analysis.Frontiers in medicine · 2026Pooled it
- Intraoperative spectral imaging versus ICG fluorescence for gastric conduit viability in esophagectomy.Surgical endoscopy · 2026Article
- Routine Intraoperative ICG Perfusion Assessment and Anastomotic Leak After Esophagectomy: A Before-After Cohort Study.Journal of clinical medicine · 2026Article
- Fluorescence imaging for assessing tissue perfusion after revascularization in peripheral arterial disease.Scientific reports · 2026Article
- SPY-QP-guided perfusion assessment to prevent esophagogastric anastomotic leakage: protocol for the SPYMIE study.BMC surgery · 2026Article
- The Role of Quantitative Indocyanine Green Angiography with Relative Perfusion Ratio in the Assessment of Gastric Conduit Perfusion in Oesophagectomy: A Retrospective Study.Journal of clinical medicine · 2025Article
- Guiding esophagectomy with intraoperative NIR-II fluorescence video imaging and rapid computation.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Article
- Fluorescein-distribution in confocal laser endomicroscopy allows for discrimination between primary brain tumours and metastases.Frontiers in surgery · 2025Article
- Current status and future trends of real-time imaging in gastric cancer surgery: A literature review.Heliyon · 2024Review
- Evaluation of the gastric conduit perfusion using indocyanine green in thoracoscopic esophagectomy for esophageal cancer.SAGE open medicine · 2024Article
- Fluorescent Imaging in Visceral Surgery: Current Opportunities and Future Perspectives.Visceral medicine · 2023Review
- Quantification of Indocyanine Green Fluorescence Imaging in General, Visceral and Transplant Surgery.Journal of clinical medicine · 2023Review
- Evaluation of the sexual function of men in Kazakhstan during 2021-2022: A cross-sectional study.Health science reports · 2023Article
Corrections and comments
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Authors and funding
9 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionAnastomotic leakage (AL) remains a prevalent and life-threatening complication after esophagectomy. Gastric tube perfusion assessment using indocyanine green fluorescence imaging (ICG-FI) has been published in several studies and appears to be a promising tool to reduce AL rates by changing the surgical approach, namely by an intraoperative evaluation of the anastomosis localization.
methodsIn this study, gastric tube perfusion was quantified by using ICG-FI in 20 high-risk patients undergoing esophagectomy. From a time-dependent fluorescence intensity curve, the following three parameters were evaluated: slope of fluorescence intensity (SFI), background subtracted peak fluorescence intensity (BSFI), and time to slope (TTS).
resultsThe values between pyloric region and tip showed a similar downward trend and SFI and BSFI significantly correlated with the distance to the pyloric region. SFI and BSFI were significantly decreased at the tip of the gastric tube. The placement of anastomosis in an area with homogenous fluorescence pattern was correlated with no AL in 92.9% of cases. An inhomogeneous fluorescence pattern at anastomotic site was a risk factor for the occurrence of an AL (p < 0.05). Reduction of perfusion up to 32% using SFI and up to 23% using BSFI was not associated with AL.
conclusionICG-FI can be used to quantify the gastric tube perfusion by calculating SFI, BSFI, and TTS. The anastomosis should be created in areas with homogeneous fluorescence pattern. A reduction in blood flow of up to 32% can be accepted without causing an increased rate of insufficiency.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.