Evidence map›Paper›PMID 35581213›Full record

ArticleScientific reports2022

Expert surgeons and deep learning models can predict the outcome of surgical hemorrhage from 1 min of video.

Dhiraj J Pangal, Guillaume Kugener, Yichao Zhu, Aditya Sinha, Vyom Unadkat, David J Cote, Ben Strickland, Martin Rutkowski, Andrew Hung, Animashree Anandkumar and 5 more

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 2 pooled it
4.6field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 2 syntheses or guidelines pooled it, 24 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
  6. Artificial Intelligence Assurance in Head and Neck Surgery: Now and Next.Proceedings. IEEE International Symposium on Computer-Based Medical Systems · 2025
    Article
  7. Article
  8. Artificial intelligence: revolutionizing robotic surgery: review.Annals of medicine and surgery (2012) · 2024
    Review
  9. Advancements in Skull Base Surgery: Navigating Complex Challenges with Artificial Intelligence.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2024
    Article
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  11. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 5 institutions in 2 countries.

Dhiraj J PangalDepartment of Neurosurgery, Keck School of Medicine of the University of Southern California, Los Angeles, CA, USA.
Guillaume KugenerDepartment of Neurosurgery, Keck School of Medicine of the University of Southern California, Los Angeles, CA, USA.
Yichao ZhuViterbi School of Engineering, University of Southern California, Los Angeles, CA, USA.
Aditya SinhaDepartment of Neurosurgery, Keck School of Medicine of the University of Southern California, Los Angeles, CA, USA.
Vyom UnadkatViterbi School of Engineering, University of Southern California, Los Angeles, CA, USA.
David J CoteDepartment of Neurosurgery, Keck School of Medicine of the University of Southern California, Los Angeles, CA, USA.
Ben StricklandDepartment of Neurosurgery, Keck School of Medicine of the University of Southern California, Los Angeles, CA, USA.
Martin RutkowskiDepartment of Neurosurgery, Medical College of Georgia, Augusta, GA, USA.
Andrew HungCenter for Robotic Simulation and Education, USC Institute of Urology, Keck School of Medicine of the University of Southern California, Los Angeles, CA, USA.
Animashree AnandkumarDepartment of Computer Science + Mathematics, California Institute of Technology, Pasadena, CA, USA.
X Y HanDepartment of Operations Research and Information Engineering, Cornell University, Ithaca, NY, USA.
Vardan PapyanDepartment of Mathematics, University of Toronto, Toronto, ON, Canada.
Bozena WrobelDepartment of Otolaryngology, Keck School of Medicine of the University of Southern California, Los Angeles, CA, USA.
Gabriel ZadaDepartment of Neurosurgery, Keck School of Medicine of the University of Southern California, Los Angeles, CA, USA.
Daniel A DonohoDivision of Neurosurgery, Center for Neuroscience, Children's National Hospital, Washington, DC, 20010, USA. danieldonohomd@gmail.com.
University of Southern California · USAugusta University · USCornell University · USNvidia (United States) · USUniversity of Toronto · CA

Funding

Mentored Career DevelopmentKL2TR001854 · NCATS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI Elizabeth Rhea Erwin Burner, Amy Elizabeth West · 2016 to 2026
$9.0M
NCATS NIH HHS KL2 TR001854
6 · The paper itself

Abstract

Major vascular injury resulting in uncontrolled bleeding is a catastrophic and often fatal complication of minimally invasive surgery. At the outset of these events, surgeons do not know how much blood will be lost or whether they will successfully control the hemorrhage (achieve hemostasis). We evaluate the ability of a deep learning neural network (DNN) to predict hemostasis control ability using the first minute of surgical video and compare model performance with human experts viewing the same video. The publicly available SOCAL dataset contains 147 videos of attending and resident surgeons managing hemorrhage in a validated, high-fidelity cadaveric simulator. Videos are labeled with outcome and blood loss (mL). The first minute of 20 videos was shown to four, blinded, fellowship trained skull-base neurosurgery instructors, and to SOCALNet (a DNN trained on SOCAL videos). SOCALNet architecture included a convolutional network (ResNet) identifying spatial features and a recurrent network identifying temporal features (LSTM). Experts independently assessed surgeon skill, predicted outcome and blood loss (mL). Outcome and blood loss predictions were compared with SOCALNet. Expert inter-rater reliability was 0.95. Experts correctly predicted 14/20 trials (Sensitivity: 82%, Specificity: 55%, Positive Predictive Value (PPV): 69%, Negative Predictive Value (NPV): 71%). SOCALNet correctly predicted 17/20 trials (Sensitivity 100%, Specificity 66%, PPV 79%, NPV 100%) and correctly identified all successful attempts. Expert predictions of the highest and lowest skill surgeons and expert predictions reported with maximum confidence were more accurate. Experts systematically underestimated blood loss (mean error - 131 mL, RMSE 350 mL, R

Indexed as

Deep LearningSurgeonsBlood Loss, SurgicalClinical CompetenceHumansReproducibility of ResultsVideo Recording

Identifiers

PMID35581213
PMCPMC9114003
OpenAlexW4280540611

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.