Evidence map›Paper›PMID 35580929›Full record

ArticleJournal for immunotherapy of cancer2022

CD4

Minglu Xiao, Luoyingzi Xie, Guoshuai Cao, Shun Lei, Pengcheng Wang, Zhengping Wei, Yuan Luo, Jingyi Fang, Xingxing Yang, Qizhao Huang and 15 more

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Journal for immunotherapy of cancer, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 41 papers.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed
5.0field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 51 citations in OpenAlex.

  1. Trial
  2. Article
  3. Review
  4. Review
  5. Article
  6. Article
  7. Review
  8. Article
  9. DCC-2036 induces repolarization of TAMs to M1 type and enhances CD8Molecular therapy : the journal of the American Society of Gene Therapy · 2026
    Article
  10. Article
  11. Tumor-embedded Immunity and TRM Cell Functions in Cancer.Mini reviews in medicinal chemistry · 2026
    Review
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Targeting tumor metabolism to augment CD8Journal of pharmaceutical analysis · 2025
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

25 authors at 8 institutions in 2 countries.

Minglu Xiao *Institute of Immunology, Third Military Medical University, Chongqing, China.
Luoyingzi Xie *Institute of Immunology, Third Military Medical University, Chongqing, China.
Guoshuai Cao *Pritzker School of Molecular Engineering, University of Chicago, Chicago, Illinois, USA.
Shun Lei *Institute of Immunology, Third Military Medical University, Chongqing, China.
Pengcheng WangKey Laboratory of Nephrology, Jinling Hospital National Clinical Research Center of Kidney Diseases, Nanjing, Jiangsu, China.
Zhengping WeiInstitute of Immunology, Third Military Medical University, Chongqing, China.
Yuan LuoDepartment of Immunology, Huazhong University of Science and Technology Tongji Medical College School of Basic Medicine, Wuhan, Hubei, China.
Jingyi FangInstitute of Immunology, Third Military Medical University, Chongqing, China.
Xingxing YangInstitute of Cancer, Third Military Medical University Second Affiliated Hospital, Chongqing, China.
Qizhao HuangSchool of Laboratory Medicine and Biotechnology, Southern Medical University, Guangzhou, Guangdong, China.
Lifan XuInstitute of Immunology, Third Military Medical University, Chongqing, China.
Junyi GuoGuangdong Provincial Key Laboratory of Stomatology, Guanghua School of Stomatology, Stomatological Hospital, Sun Yat-Sen University, Guangzhou, Guangdong, China.
Shuqiong WenGuangdong Provincial Key Laboratory of Stomatology, Guanghua School of Stomatology, Stomatological Hospital, Sun Yat-Sen University, Guangzhou, Guangdong, China.
Zhiming WangInstitute of Immunology, Third Military Medical University, Chongqing, China.
Qing WuInstitute of Immunology, Third Military Medical University, Chongqing, China.
Jianfang TangInstitute of Immunology, Third Military Medical University, Chongqing, China.
Lisha WangInstitute of Immunology, Third Military Medical University, Chongqing, China.
Xiangyu ChenSchool of Laboratory Medicine and Biotechnology, Southern Medical University, Guangzhou, Guangdong, China.
Cheng ChenInstitute of Immunology, Third Military Medical University, Chongqing, China.
Yanyan ZhangInstitute of Hepatopancreatobiliary Surgery, Chongqing General Hospital, University of Chinese Academy of Sciences, Chongqing, China.
Wei YaoInstitute of Immunology, Third Military Medical University, Chongqing, China.
Jianqiang YeKey Laboratory of Jiangsu Preventive Veterinary Medicine, Key Laboratory for Avian Preventive Medicine, Ministry of Education, College of Veterinary Medicine, Yangzhou University, Yangzhou, Jiangsu, China yelilinlcmv@163.com huangjun@uchicago.edu ranhe@hust.edu.cn jqye@yzu.edu.cn.
Ran HeDepartment of Immunology, Huazhong University of Science and Technology Tongji Medical College School of Basic Medicine, Wuhan, Hubei, China yelilinlcmv@163.com huangjun@uchicago.edu ranhe@hust.edu.cn jqye@yzu.edu.cn.
Jun HuangPritzker School of Molecular Engineering, University of Chicago, Chicago, Illinois, USA yelilinlcmv@163.com huangjun@uchicago.edu ranhe@hust.edu.cn jqye@yzu.edu.cn.ORCID 0000-0003-0271-4384
Lilin YeInstitute of Immunology, Third Military Medical University, Chongqing, China yelilinlcmv@163.com huangjun@uchicago.edu ranhe@hust.edu.cn jqye@yzu.edu.cn.ORCID 0000-0003-0778-3311
Army Medical University · CNHuazhong University of Science and Technology · CNSouthern Medical University · CNStomatology Hospital · CNUniversity of Chicago · USNanjing General Hospital of Nanjing Military Command · CNUniversity of Chinese Academy of Sciences · CNYangzhou University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAntitumor therapeutic vaccines are generally based on antigenic epitopes presented by major histocompatibility complex (MHC-I) molecules to induce tumor-specific CD8

methods

resultsCD4

conclusionCD4

Indexed as

AdenocarcinomaColorectal NeoplasmsMelanomaAnimalsB7-H1 AntigenCD4-Positive T-LymphocytesCD8-Positive T-LymphocytesEpitopes, T-LymphocyteGlycoproteinsHumansImmune Checkpoint InhibitorsImmunotherapyMiceOvalbuminProgrammed Cell Death 1 ReceptorReceptors, Antigen, T-CellB7-H1 AntigenEpitopes, T-LymphocyteGlycoproteinsImmune Checkpoint InhibitorsOvalbuminProgrammed Cell Death 1 ReceptorReceptors, Antigen, T-CellCD4-Positive T-LymphocytesCD8-Positive T-LymphocytesImmunizationImmunotherapyVaccination

Identifiers

PMID35580929
PMCPMC9114852
OpenAlexW4280517325

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.