Evidence map›Paper›PMID 35580910›Full record

ArticleRespiratory care2022

High-Frequency Percussive Ventilation in Viral Bronchiolitis.

Benjamin R White, Noelle Cadotte, Eric B McClellan, Angela P Presson, Erin Bennett, Andrew G Smith, Salim Aljabari

Open access · bronzeAbstract readEditorial
In one paragraph

Article in Respiratory care, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 1 country.

Benjamin R WhiteDepartment of Pediatrics, Division of Pediatric Critical Care, Penn State Health Children's Hospital, Hershey, Pennsylvania. benjaminrobertwhite@gmail.com.
Noelle CadotteDepartment of Pediatrics, Division of Pediatric Critical Care, University of Utah, Salt Lake City, Utah.
Eric B McClellanDepartment of Pediatrics, Division of Cardiology, University of Michigan, Ann Arbor, Michigan.
Angela P PressonDepartment of Internal Medicine, Division of Epidemiology, University of Utah, Salt Lake City, Utah.
Erin BennettDepartment of Pediatrics, Division of Critical Care, University of Arkansas for Medical Sciences, Little Rock, Arkansas.
Andrew G SmithDepartment of Pediatrics, Division of Pediatric Critical Care, University of Utah, Salt Lake City, Utah.
Salim AljabariDepartment of Pediatrics, Division of Pediatric Critical Care, University of Missouri, Columbia, Missouri.
University of Utah · USPenn State Milton S. Hershey Medical Center · USUniversity of Arkansas Medical Center · USUniversity of Michigan · USUniversity of Missouri Health System · US

Funding

University of Utah Center for Clinical and Translational ScienceUL1TR001067 · NCATS · UNIVERSITY OF UTAH · PI DERE, WILLARD H., HESS, RACHEL · 2013 to 2017
$19.8M
UNIVERSITY OF UTAH CENTER FOR CLINICAL AND TRANSLATIONAL SCIENCE-UL1: BPCAUL1RR025764 · NCRR · UNIVERSITY OF UTAH · PI MCCLAIN, DONALD A. · 2008 to 2011
$19.4M
University of Utah Center for Clinical and Translational Science-UL1UL1TR000105 · NCATS · UNIVERSITY OF UTAH · PI MCCLAIN, DONALD A. · 2012 to 2013
$5.1M
NCATS NIH HHS UL1 TR000105NCATS NIH HHS UL1 TR001067NCRR NIH HHS UL1 RR025764
6 · The paper itself

Abstract

backgroundHigh-frequency percussive ventilation (HFPV) is an alternative mode of mechanical ventilation that has been shown to improve gas exchange in subjects with severe respiratory failure. We hypothesized that HFPV use would improve ventilation and oxygenation in intubated children with acute bronchiolitis.

methodsIn this single-center prospective cohort study we included mechanically ventilated children in the pediatric ICU with bronchiolitis 1-24 months old who were transitioned to HFPV from conventional invasive mechanical ventilation from November 2018-April 2020. Patients with congenital heart disease, on extracorporeal membrane oxygenation (ECMO), and with HFPV duration < 12 h were excluded. Subject gas exchange metrics and ventilator parameters were compared before and after HFPV initiation.

resultsForty-one of 192 (21%) patients intubated with bronchiolitis underwent HFPV, and 35 met inclusion criteria. Median age of cohort was 4 months, and 60% were previously healthy. All subjects with available oxygenation saturation index (OSI) measurements pre-HFPV met pediatric ARDS criteria (31/35, 89%). Mean CO

conclusionsHFPV was associated with significant improvement in ventilation and decreased exposure to high PIPs for mechanically ventilated children with bronchiolitis in our cohort and had a potential association with improved oxygenation. Our study shows that HFPV may be an effective alternative mode of ventilation in patients with bronchiolitis who have poor gas exchange on conventional invasive mechanical ventilation.

Indexed as

Bronchiolitis, ViralHigh-Frequency VentilationRespiratory Distress SyndromeChildChild, PreschoolHumansInfantProspective StudiesRespiration, Artificialacute bronchiolitishigh-frequency percussive ventilationmechanical ventilationpediatric ARDSpediatric ICU

Identifiers

PMID35580910
PMCPMC9994098
OpenAlexW4280522283

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.