ArticleThe journals of gerontology. Series A, Biological sciences and medical sciences2022
Thigh Muscle Composition and Its Relationship to Functional Recovery Post Hip Fracture Over Time and Between Sexes.
Article in The journals of gerontology. Series A, Biological sciences and medical sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.
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Who cites it
6 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.
- Feasibility, acceptability and prognostic value of muscle mass and strength measurement in patients with hip fracture: a systematic review.European geriatric medicine · 2024Pooled it
- Association between chronic inflammation and poorer long-term functional recovery post-hip fracture in and between men and women.JBMR plus · 2026Article
- Artificial intelligence-driven assessment of sarcopenia in orthopedic geriatrics: technical progress and clinical implications.Frontiers in endocrinology · 2026Review
- Relationship between muscle size and density and proximal femoral bone mineral density in elderly men with hip fractures across different age groups.Journal of orthopaedic surgery and research · 2025Article
- Related factors of postoperative half-year care utilization for health status and recovery in older adults with hip fracture: A retrospective study of Osaka National Health Insurance Data.Geriatrics & gerontology international · 2025Article
- Shape phenotype of thigh fat and muscle and risk of major adverse cardiovascular events after fragility hip fracture.Journal of cachexia, sarcopenia and muscle · 2024Article
Corrections and comments
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Authors and funding
7 authors at 4 institutions in 1 country.
Funding
Abstract
backgroundComputed tomography (CT)-scan measures of muscle composition may be associated with recovery post hip fracture.
methodsIn an ancillary study to Baltimore Hip Studies Seventh cohort, older adults were evaluated at 2 and 6 months post hip fracture. CT-scan measures of muscle were acquired at 2 months. Short Physical Performance Battery (SPPB) was measured at 2 and 6 months. Generalized estimating equations were used to model the association of muscle measures and physical function, adjusting for age, sex, body mass index, and time postfracture.
resultsSeventy-one older adults (52% males, age 79.6 ± 7.3 years) were included. At 2-months, males had greater thigh cross-sectional area (CSA, p < .0001) and less low-density muscle (p = .047), and intermuscular adipose tissue (p = .007) than females on the side of the fracture, while females performed better on the SPPB (p = .05). Muscle measures on the fractured side were associated with function at 2 months in both sexes. Participants with the lowest tertile of muscle CSA difference at 2-months, indicating greater symmetry in CSA between limbs, performed better than the other 2 tertiles at 6-months. Males performed worse in functional measures at baseline and did not recover as well as females (p = .02).
conclusionCT-scan measures of muscle CSA and fatty infiltration were associated with function at 2-months post hip fracture and with improvement in function by 6 months. Observed sex differences in these associations suggest that rehabilitation strategies may need to be adapted by sex after hip fracture.
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