Evidence map›Paper›PMID 35580792›Full record

ArticleBrain, behavior, and immunity2022

T-lymphocyte tyrosine hydroxylase regulates T

Safwan K Elkhatib, Cassandra M Moshfegh, Gabrielle F Watson, Adam J Case

Open access · hybridAbstract read
In one paragraph

Article in Brain, behavior, and immunity, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
3.0field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 27 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Beta Adrenergic Signaling as a Therapeutic Target for Autoimmunity.bioRxiv : the preprint server for biology · 2025
    Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Review
  11. TBrain, behavior, and immunity · 2025
    Article
  12. Article
  13. Article
  14. Neurobehavioral Characterization of Perinatal Oxycodone-Exposed Offspring in Early Adolescence.Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology · 2024
    Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. S100a9 Protects Against the Effects of Repeated Social Defeat Stress.Biological psychiatry global open science · 2023
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Safwan K ElkhatibDepartment of Cellular and Integrative Physiology, College of Medicine, University of Nebraska Medical Center, Omaha, Nebraska, United States.
Cassandra M MoshfeghDepartment of Cellular and Integrative Physiology, College of Medicine, University of Nebraska Medical Center, Omaha, Nebraska, United States.
Gabrielle F WatsonDepartment of Cellular and Integrative Physiology, College of Medicine, University of Nebraska Medical Center, Omaha, Nebraska, United States.
Adam J CaseDepartment of Psychiatry and Behavioral Sciences, Texas A&M Health Science Center, College Station, TX, United States; Department of Medical Physiology, Texas A&M Health Science Center, College Station, TX, United States. Electronic address: acase@tamu.edu.
University of Nebraska Medical Center · USTexas A&M Health Science Center · US

Funding

Neuroimmune dynamics involved in the pathogenesis of hypertension after psychological traumaR01HL158521 · NHLBI · TEXAS A&M UNIVERSITY HEALTH SCIENCE CTR · PI CASE, ADAM J · 2021 to 2025
$2.7M
Neuroimmune contributions to hypertension sensitization in a preclinical model of PTSDF30HL154535 · NHLBI · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI ELKHATIB, SAFWAN KIJANA · 2020 to 2023
$162k
NHLBI NIH HHS F30 HL154535NHLBI NIH HHS R01 HL158521
6 · The paper itself

Abstract

Posttraumatic stress disorder (PTSD) is a debilitating psychiatric disorder which results in deleterious changes to psychological and physical health. Patients with PTSD are especially susceptible to life-threatening co-morbid inflammation-driven pathologies, such as autoimmunity, while also demonstrating increased T-helper 17 (T

Indexed as

Interleukin-17Tyrosine 3-MonooxygenaseAnimalsCatecholaminesHumansInflammationMiceSocial DefeatSuperoxidesTh17 CellsCatecholaminesInterleukin-17SuperoxidesTyrosine 3-MonooxygenaseCatecholamineCytokineIL-17IL-22PTSDSuperoxideT-cell

Identifiers

PMID35580792
PMCPMC9659669
OpenAlexW4280522181

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.