ArticleResuscitation2022
Acute respiratory distress syndrome after in-hospital cardiac arrest.
Article in Resuscitation, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed, 35 citations in OpenAlex.
- Computed tomography assessment after out-of-hospital cardiac arrest resuscitation.Resuscitation plus · 2026Article
- Ventilation parameters during adult cardiopulmonary resuscitation: a systematic review.Resuscitation plus · 2026Article
- [Cardiac resuscitation-associated lung edema (CRALE): evaluation of diagnostic and therapeutic approaches by an expert group of the German Cardiac Society].Medizinische Klinik, Intensivmedizin und Notfallmedizin · 2026Article
- Fluid management strategies in critically ill patients with ARDS: a narrative review.European journal of medical research · 2025Review
- Monocyte programmed death-ligand 1 upregulation in early post-out-of-hospital cardiac arrest is associated with increased risk of acute respiratory distress syndrome.Resuscitation plus · 2024Article
- Ventilation and Oxygenation During and After Adult Cardiopulmonary Resuscitation: Changing Paradigms.Respiratory care · 2024Review
- Acute lung injury and post-cardiac arrest syndrome: a narrative review.Journal of intensive care · 2024Review
- Extracerebral multiple organ dysfunction and interactions with brain injury after cardiac arrest.Resuscitation plus · 2024Review
- [Influence of the no flow time on lung edema in the postresuscitation phase].Medizinische Klinik, Intensivmedizin und Notfallmedizin · 2024Article
- Cardiac arrest related lung edema: examining the role of downtimes in transpulmonary thermodilution analysis.Internal and emergency medicine · 2024Article
- Inflammation, endothelial injury, and the acute respiratory distress syndrome after out-of-hospital cardiac arrest.Resuscitation plus · 2024Article
- Critical Care Management of Patients After Cardiac Arrest: A Scientific Statement from the American Heart Association and Neurocritical Care Society.Neurocritical care · 2024Article
- Critical Care Management of Patients After Cardiac Arrest: A Scientific Statement From the American Heart Association and Neurocritical Care Society.Circulation · 2024Review
- Heart-lung crosstalk in acute respiratory distress syndrome.Frontiers in physiology · 2024Review
- Exploration of alive-and-ventilator free days as an outcome measure for clinical trials of Resuscitative interventions.PloS one · 2024Article
- Continuous chest compressions are associated with higher peak inspiratory pressures when compared to 30:2 in an experimental cardiac arrest model.Intensive care medicine experimental · 2023Article
- Benefits, key protocol components, and considerations for successful implementation of extracorporeal cardiopulmonary resuscitation: a review of the recent literature.Clinical and experimental emergency medicine · 2023Article
- Respiratory challenges and ventilatory management in different types of acute brain-injured patients.Critical care (London, England) · 2023Review
- Acute Respiratory Distress Syndrome in Patients with Cardiovascular Disease.Methodist DeBakey cardiovascular journal · 2023Review
- Don't go breaking my…lungs? The acute respiratory distress syndrome is common, deadly, and probably underrecognized after cardiac arrest.Resuscitation · 2022Article
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
Abstract
objectiveAcute respiratory distress syndrome (ARDS) after out-of-hospital cardiac arrest is common and associated with worse outcomes. In the hospital setting, there are many potential risk factors for post-arrest ARDS, such as aspiration, sepsis, and shock. ARDS after in-hospital cardiac arrest (IHCA) has not been characterized.
methodsWe performed a single-center retrospective study of adult patients admitted to the hospital between 2014-2018 who suffered an IHCA, achieved return of spontaneous circulation (ROSC), and were either already intubated at the time of arrest or within 2 hours of ROSC. Post-IHCA ARDS was defined as meeting the Berlin criteria in the first 3 days following ROSC. Outcomes included alive-and-ventilator free days across 28 days, hospital length-of-stay, hospital mortality, and hospital disposition.
resultsOf 203 patients included, 146 (71.9%) developed ARDS. In unadjusted analysis, patients with ARDS had fewer alive-and-ventilator-free days over 28 days with a median of 1 (IQR: 0, 21) day, compared to 18 (IQR: 0, 25) days in patients without ARDS (p = 0.03). However, this association was not significant after multivariate adjustment. There was also a non-significant longer hospital length-of-stay (15 [IQR: 7, 26] vs 10 [IQR: 7, 22] days, p = 0.25; median adjusted increase in ARDS patients: 3 [95% CI: -2 to 8] days, p = 0.27) and higher hospital mortality (53% vs 44%, p = 0.26; aOR 1.6 [95% CI: 0.8-2.9], p = 0.17) in the ARDS group.
conclusionAmong IHCA patients, almost three-quarters developed ARDS within 3 days of ROSC. As in out of hospital cardiac arrest, post-IHCA ARDS is common.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.