ArticleRespirology (Carlton, Vic.)2022
Sleep-disordered breathing was associated with lower health-related quality of life and cognitive function in a cross-sectional study of older adults.
Article in Respirology (Carlton, Vic.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.
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Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.
- Non-pharmacological interventions for sleep in older adults: an umbrella review and evidence map of randomized controlled trials.Frontiers in neurology · 2025Pooled it
- Trial
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- Impact of sleep apnea on alzheimer's disease in relation to sex: an 8-year longitudinal follow-up study of a nationwide cohort.Alzheimer's research & therapy · 2025Article
- Sleep apnoea, cognition and aspirin's effects in healthy older people: an ASPREE substudy.ERJ open research · 2025Article
- Obstructive sleep apnea, cognitive impairment, and dementia: is sleep microstructure an important feature?Sleep · 2024Article
- Nocturnal hypoxia and age-related macular degeneration.Clinical & experimental ophthalmology · 2024Article
- Level 2 Polysomnography for the Diagnosis of Sleep Disorders: A Health Technology Assessment.Ontario health technology assessment series · 2024Article
- Sleep-disordered breathing was associated with lower health-related quality of life and cognitive function in a cross-sectional study of older adults.Respirology (Carlton, Vic.) · 2022Article
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16 authors at 7 institutions in 3 countries.
Funding
Abstract
BACKGROUND AND
objectiveThe clinical significance of sleep-disordered breathing (SDB) in older age is uncertain. This study determined the prevalence and associations of SDB with mood, daytime sleepiness, quality of life (QOL) and cognition in a relatively healthy older Australian cohort.
methodsA cross-sectional analysis was conducted from the Study of Neurocognitive Outcomes, Radiological and retinal Effects of Aspirin in Sleep Apnoea. Participants completed an unattended limited channel sleep study to measure the oxygen desaturation index (ODI) to define mild (ODI 5-15) and moderate/severe (ODI ≥ 15) SDB, the Centre for Epidemiological Studies Scale, the Epworth Sleepiness Scale, the 12-item Short-Form for QOL and neuropsychological tests.
resultsOf the 1399 participants (mean age 74.0 years), 36% (273 of 753) of men and 25% (164 of 646) of women had moderate/severe SDB. SDB was associated with lower physical health-related QOL (mild SDB: beta coefficient [β] -2.5, 95% CI -3.6 to -1.3, p < 0.001; moderate/severe SDB: β -1.8, 95% CI -3.0 to -0.6, p = 0.005) and with lower global composite cognition (mild SDB: β -0.1, 95% CI -0.2 to 0.0, p = 0.022; moderate/severe SDB: β -0.1, 95% CI -0.2 to 0.0, p = 0.032) compared to no SDB. SDB was not associated with daytime sleepiness nor depression.
conclusionSDB was associated with lower physical health-related quality of life and cognitive function. Given the high prevalence of SDB in older age, assessing QOL and cognition may better delineate subgroups requiring further management, and provide useful treatment target measures for this age group.
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