Evidence map›Paper›PMID 35579949›Full record

ArticleJournal of neurotrauma2022

Diffusion Tensor Imaging Reveals Elevated Diffusivity of White Matter Microstructure that Is Independently Associated with Long-Term Outcome after Mild Traumatic Brain Injury: A TRACK-TBI Study.

Eva M Palacios, Esther L Yuh, Christine L Mac Donald, Ioanna Bourla, Jamie Wren-Jarvis, Xiaoying Sun, Mary J Vassar, Ramon Diaz-Arrastia, Joseph T Giacino, David O Okonkwo and 10 more

Open access · hybridAbstract read
In one paragraph

Article in Journal of neurotrauma, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed, 1 pooled it
8.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 1 synthesis or guideline pooled it, 64 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

20 authors at 9 institutions in 1 country.

Eva M PalaciosDepartment of Radiology and Biomedical Imaging, UCSF, San Francisco, California, USA.
Esther L YuhDepartment of Radiology and Biomedical Imaging, UCSF, San Francisco, California, USA.
Christine L Mac DonaldDepartment of Neurological Surgery, University of Washington, Seattle, Washington, USA.
Ioanna BourlaDepartment of Radiology and Biomedical Imaging, UCSF, San Francisco, California, USA.
Jamie Wren-JarvisDepartment of Radiology and Biomedical Imaging, UCSF, San Francisco, California, USA.
Xiaoying SunBiostatistics Research Center, Herbert Wertheim School of Public Health and Human Longevity Science, University of California, San Diego, La Jolla, California, USA.
Mary J VassarBrain and Spinal Cord Injury Center, Zuckerberg San Francisco General Hospital and Trauma Center, San Francisco, California, USA.
Ramon Diaz-ArrastiaDepartment of Neurology, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Joseph T GiacinoDepartment of Physical Medicine and Rehabilitation, Spaulding Rehabilitation Hospital, Charlestown, Massachusetts, USA.
David O OkonkwoDepartment of Neurological Surgery, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA.
Claudia S RobertsonDepartment of Neurosurgery, Baylor College of Medicine, Houston, Texas, USA.
Murray B SteinBiostatistics Research Center, Herbert Wertheim School of Public Health and Human Longevity Science, University of California, San Diego, La Jolla, California, USA.
Nancy TemkinDepartment of Neurological Surgery, University of Washington, Seattle, Washington, USA.
Michael A McCreaDepartment of Neurosurgery and Neurology, Medical College of Wisconsin, Milwaukee, Wisconsin, USA.
Harvey S LevinDepartment of Neurology, Baylor College of Medicine, Houston, Texas, USA.
Amy J MarkowitzDepartment of Neurological Surgery, University of Washington, Seattle, Washington, USA.
Sonia JainBiostatistics Research Center, Herbert Wertheim School of Public Health and Human Longevity Science, University of California, San Diego, La Jolla, California, USA.
Geoffrey T ManleyDepartment of Neurological Surgery, University of Washington, Seattle, Washington, USA.
Pratik MukherjeeDepartment of Radiology and Biomedical Imaging, UCSF, San Francisco, California, USA.
TRACK-TBI Investigators
San Francisco General Hospital · USUniversity of Washington · USBaylor College of Medicine · USHuman Longevity (United States) · USUniversity of Pittsburgh Medical Center · USHarvard University · USMedical College of Wisconsin · USUniversity of California San Diego · USUniversity of Pennsylvania · US

Funding

Transforming Research and Clinical Knowledge in Traumatic Brain InjuryU01NS086090 · NINDS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI DIAZ-ARRASTIA, RAMON, GIACINO, JOSEPH THOMAS · 2013 to 2017
$19.1M
NINDS NIH HHS U01 NS086090
6 · The paper itself

Abstract

Diffusion tensor imaging (DTI) literature on single-center studies contains conflicting results regarding acute effects of mild traumatic brain injury (mTBI) on white matter (WM) microstructure and the prognostic significance. This larger-scale multi-center DTI study aimed to determine how acute mTBI affects WM microstructure over time and how early WM changes affect long-term outcome. From Transforming Research and Clinical Knowledge in Traumatic Brain Injury (TRACK-TBI), a cohort study at 11 United States level 1 trauma centers, a total of 391 patients with acute mTBI ages 17 to 60 years were included and studied at two weeks and six months post-injury. Demographically matched friends or family of the participants were the control group (

Indexed as

Brain ConcussionBrain Injuries, TraumaticWhite MatterAdolescentAdultBrainCohort StudiesDiffusion Magnetic Resonance ImagingDiffusion Tensor ImagingHumansMiddle AgedYoung Adultconcussiondiffusion tensor imagingGlasgow Outcome ScaleMRItraumatic brain injury

Identifiers

PMID35579949
PMCPMC9529303
OpenAlexW4280491213

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.