Evidence map›Paper›PMID 35579928›Full record

ArticleJMIR research protocols2022

Cardiovascular Disease Prevention Education Using a Virtual Environment in Sexual-Minority Men of Color With HIV: Protocol for a Sequential, Mixed Method, Waitlist Randomized Controlled Trial.

S Raquel Ramos, Constance Johnson, Gail Melkus, Trace Kershaw, Marya Gwadz, Harmony Reynolds, Allison Vorderstrasse

Registry-linked trialAbstract read
In one paragraph

Article in JMIR research protocols, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05242952 (LEveraging A viRtual eNvironment), which is not on this map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05242952 nacompletednot on this mapstarted 2023, after this paper: background citation

LEveraging A viRtual eNvironment (LEARN) to Enhance Prevention of HIV-related Comorbidities in At-risk Minority MSM

TypeinterventionalSponsorYale UniversityRan2023 to 2025Enrolled78ConditionsCardiovascular DiseasesArmsGaming in a virtual environment
3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Trial
  2. Trial
  3. Sexual identity differences in ideal cardiovascular health among cisgender adults in the All of Us Research Program.Annals of behavioral medicine : a publication of the Society of Behavioral Medicine · 2025
    Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

S Raquel Ramos *School of Nursing, Yale University, Orange, CT, United States.ORCID https://orcid.org/0000-0003-2403-7222
Constance Johnson *Cizik School of Nursing, University of Texas Houston, Houston, TX, United States.ORCID https://orcid.org/0000-0003-3162-3932
Gail Melkus *Rory Meyers College of Nursing, New York University, New York, NY, United States.ORCID https://orcid.org/0000-0002-5859-4118
Trace Kershaw *Department of Social and Behavioral Sciences, School of Public Health, Yale University, New Haven, CT, United States.ORCID https://orcid.org/0000-0002-3300-1355
Marya Gwadz *The Center for Drug Use and HIV Research, New York University, New York, NY, United States.ORCID https://orcid.org/0000-0002-2386-9409
Harmony Reynolds *Department of Medicine, Grossman School of Medicine, New York University, New York, NY, United States.ORCID https://orcid.org/0000-0003-0284-0655
Allison Vorderstrasse *Elaine Marieb College of Nursing, University of Massachusetts Amherst, Amherst, MA, United States.ORCID https://orcid.org/0000-0001-8770-1851

Funding

Program to Increase Diversity in Cardiovascular Health-Related Research(PRIDE-CVD)R25HL105446 · NHLBI · SUNY DOWNSTATE MEDICAL CENTER · PI Mohamed Boutjdir · 2010 to 2026
$5.9M
Research Education Institute for Dynamic Scholars (REIDS)R25MH087217 · NIMH · YALE UNIVERSITY · PI Jasmine Abrams, Trace S Kershaw · 2010 to 2026
$3.9M
LEveraging A viRtual eNvironment (LEARN) to Enhance Prevention of HIV-related Comorbidities, SupplementK01HL145580 · NHLBI · YALE UNIVERSITY · PI RAMOS, SILVIA RAQUEL · 2019 to 2023
$860k
BLRD VA I01 BX002137NHLBI NIH HHS K01 HL145580NHLBI NIH HHS L30 HL149001NHLBI NIH HHS R25 HL105446NIMH NIH HHS R25 MH087217
6 · The paper itself

Abstract

backgroundIt is estimated that 70% of all deaths each year in the United States are due to chronic conditions. Cardiovascular disease (CVD), a chronic condition, is the leading cause of death in ethnic and racial minority males. It has been identified as the second most common cause of death in persons with HIV. By the year 2030, it is estimated that 78% of persons with HIV will be diagnosed with CVD.

objectiveWe propose the first technology-based virtual environment intervention to address behavioral, modifiable risk factors associated with cardiovascular and metabolic comorbidities in sexual-minority men of color with HIV.

methodsThis study will be guided using social cognitive theory and the Technology Acceptance Model. A sequential, mixed method, waitlist controlled randomized control feasibility trial will be conducted. Aim 1 is to qualitatively explore perceptions of cardiovascular risk in 15 participants. Aim 2 is to conduct a waitlist controlled comparison to test if a virtual environment is feasible and acceptable for CVD prevention, based on web-based, self-assessed, behavioral, and psychosocial outcomes in 80 sexual-minority men of color with HIV.

resultsThe study was approved by the New York University Institutional Review Board in 2019, University of Texas Health Science Center at Houston in 2020, and by the Yale University Institutional Review Board in February 2022. As of April 2022, aim 1 data collection is 87% completed. We expect to complete data collection for aim 1 by April 30, 2022. Recruitment for aim 2 will begin mid-May 2022.

conclusionsThis study will be the first online virtual environment intervention for CVD prevention in sexual-minority men of color with HIV. We anticipate that the intervention will be beneficial for CVD prevention education and building peer social supports, resulting in change or modification over time in risk behaviors for CVD.

trial registrationClinicalTrials.gov NCT05242952; https://clinicaltrials.gov/ct2/show/NCT05242952. INTERNATIONAL REGISTERED REPORT IDENTIFIER (IRRID): PRR1-10.2196/38348.

Indexed as

behavioral interventioncardiovascular diseaseconsumer health informaticsgamificationhealth communicationHIVprevention educationsexual minority menvirtual environment

Identifiers

PMID35579928
PMCPMC9157319

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.