Evidence map›Paper›PMID 35579717›Full record

ArticleArchives of microbiology2022

Antifungal activity screening of fractions from Annona cherimola Mill. leaf extract against Fusarium oxysporum.

Manuel Méndez-Chávez, Carlos A Ledesma-Escobar, Madeleine Hidalgo-Morales, Guadalupe Del Carmen Rodríguez-Jimenes, Victor José Robles-Olvera

Abstract read
PubMed Publisher
In one paragraph

Article in Archives of microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.2field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Latin American Plants against Microorganisms.Plants (Basel, Switzerland) · 2023
    Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Manuel Méndez-ChávezTecnológico Nacional de México/Instituto Tecnológico de Veracruz, Unidad de Investigación y Desarrollo en Alimentos, Miguel Ángel de Quevedo 2779, Colonia Formando Hogar, 91897, Veracruz, VER, México.
Carlos A Ledesma-EscobarDepartment of Analytical Chemistry, Campus of Rabanales, University of Cordoba, Madrid, Spain.
Madeleine Hidalgo-MoralesTecnológico Nacional de México/Instituto Tecnológico de Veracruz, Unidad de Investigación y Desarrollo en Alimentos, Miguel Ángel de Quevedo 2779, Colonia Formando Hogar, 91897, Veracruz, VER, México.
Guadalupe Del Carmen Rodríguez-JimenesTecnológico Nacional de México/Instituto Tecnológico de Veracruz, Unidad de Investigación y Desarrollo en Alimentos, Miguel Ángel de Quevedo 2779, Colonia Formando Hogar, 91897, Veracruz, VER, México.
Victor José Robles-OlveraTecnológico Nacional de México/Instituto Tecnológico de Veracruz, Unidad de Investigación y Desarrollo en Alimentos, Miguel Ángel de Quevedo 2779, Colonia Formando Hogar, 91897, Veracruz, VER, México. victor.ro@veracruz.tecnm.mx.ORCID http://orcid.org/0000-0002-8492-9022
Tecnológico Nacional de México · MXInstituto de Salud Carlos III · ES

Funding

Tecnológico Nacional de México Grant No. TecNM-5915.16-PTecnológico Nacional de México Grant No. TecnNM-6851.18-P)
6 · The paper itself

Abstract

The antifungal effect of ethanolic extract fractions of Annona cherimola leaves against the mycelial growth of Fusarium oxysporum was studied. The ethanolic crude extract was solvent partitioned and the ethyl acetate phase was fractionated by column or preparative thin-layer chromatography. All fractions were developed on TLC and analyzed for acetogenins (ACG) with Kedde reagent. The antifungal effect assays were carried out in vitro by the diffusion method on PDA plates. The ethanolic extract of A. cherimola leaves was highly active against F. oxysporum growth; subfractions obtained from the antifungal screening had a significant effect (p < 0.05) on the F. oxysporum growth parameters. The screening showed that as the purification steps progressed, the inhibition of mycelial growth increased. Six bioactive ACG (Annomolon-B, 34-epi annomolon B, almunequin, cherimoline 1, cherimoline 2, and isocherimoline 1) were identified by LC-QTOF-MS/MS. These findings suggested that bioactive ACG from A. cherimola leaves could be an alternative resource of a promising botanical fungicide to control plant diseases caused by F. oxysporum.

Indexed as

AnnonaFusariumAntifungal AgentsPlant ExtractsTandem Mass SpectrometryAntifungal AgentsPlant ExtractsAcetogeninsAnnona cherimola Mill.Antifungal activityPhytopathogenic fungiScreening antifungal

Identifiers

PMID35579717
OpenAlexW4280544108

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.