Evidence map›Paper›PMID 35579676›Full record

ArticleAnalytical and bioanalytical chemistry2022

Biomass-derived carbon dots as a sensitive and selective dual detection platform for fluoroquinolones and tetracyclines.

Binila K Korah, Anu Rose Chacko, Sneha Mathew, Bony K John, Thomas Abraham, Beena Mathew

Abstract read
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Article in Analytical and bioanalytical chemistry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
4.4field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 61 citations in OpenAlex.

  1. Review
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  11. Biomass-Derived Carbon Dots and Their Sensing Applications.Nanomaterials (Basel, Switzerland) · 2022
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Binila K KorahSchool of Chemical Sciences, Mahatma Gandhi University, Priyadarsini Hills P. O., Kottayam, 686 560, Kerala, India.
Anu Rose ChackoSchool of Chemical Sciences, Mahatma Gandhi University, Priyadarsini Hills P. O., Kottayam, 686 560, Kerala, India.
Sneha MathewSchool of Chemical Sciences, Mahatma Gandhi University, Priyadarsini Hills P. O., Kottayam, 686 560, Kerala, India.
Bony K JohnSchool of Chemical Sciences, Mahatma Gandhi University, Priyadarsini Hills P. O., Kottayam, 686 560, Kerala, India.
Thomas AbrahamSchool of Chemical Sciences, Mahatma Gandhi University, Priyadarsini Hills P. O., Kottayam, 686 560, Kerala, India.
Beena MathewSchool of Chemical Sciences, Mahatma Gandhi University, Priyadarsini Hills P. O., Kottayam, 686 560, Kerala, India. beenamathew@mgu.ac.in.
Mahatma Gandhi University · INUniversity of Kerala · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A novel carbon dot (CD) was synthesized through the facile and simple hydrothermal method from Curcuma amada, as the precursor for the first time. These CDs with an average diameter of 4.6 nm display blue fluorescence, with excitation/emission maxima at 360/445 nm and a quantum yield of 14.1%. It exhibited high stability under different conditions and was characterized using various techniques. These CDs can be employed as a dual-sensing platform to detect tetracyclines and fluoroquinolones, two antibiotic classes. Even though antibiotics are regarded as an inevitable commodity, overuse and improper management of discarded antibiotics pose a severe threat to the environment. Herein, we developed a dual-sensing, biocompatible sensor with high selectivity and sensitivity to detect antibiotics. CD was employed as a fluorescence probe and detected tetracycline and fluoroquinolone antibiotic through inner filter effect-based fluorescence quenching and hydrogen bonding-based enhancement process, respectively. The linear range was 0-16 μM and the detection limit was 33 nM for tetracycline and 2 nM for fluoroquinolone antibiotic. As an electrochemical probe, CD selectively detected tetracycline with a lower detection limit of 0.5 nM over a linear range of 0-16 μM. Using both methods, a real sample analysis of the developed sensor exhibited accurate reliability and precision.

Indexed as

Quantum DotsTetracyclinesAnti-Bacterial AgentsBiomassCarbonFluorescent DyesFluoroquinolonesReproducibility of ResultsSpectrometry, FluorescenceTetracyclineAnti-Bacterial AgentsCarbonFluorescent DyesFluoroquinolonesTetracyclineTetracyclinesCarbon dotCurcuma amadaElectrochemical analysisFluorescenceFluoroquinolonesTetracyclines

Identifiers

PMID35579676
OpenAlexW4280522223

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.