Trial reportAmerican journal of respiratory and critical care medicine2022
Cardiovascular Benefit of Continuous Positive Airway Pressure in Adults with Coronary Artery Disease and Obstructive Sleep Apnea without Excessive Sleepiness.
Open access · greenAbstract readRandomized Controlled Trial
In one paragraph
Trial report in American journal of respiratory and critical care medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 65 papers, 1 of them a synthesis that pooled it.
0numbers the graph read from it
0cells of the map it votes in
65citing papers in PubMed, 1 pooled it
9.3field-weighted citation impact, top 1% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
65 citing papers in PubMed, 1 synthesis or guideline pooled it, 89 citations in OpenAlex.
- Positive airway pressure therapy and all-cause and cardiovascular mortality in people with obstructive sleep apnoea: a systematic review and meta-analysis of randomised controlled trials and confounder-adjusted, non-randomised controlled studies.The Lancet. Respiratory medicine · 2025Pooled it
- Trial
- Propranolol mitigates sleep apnea-related cardiac responses during CPAP withdrawal: a randomized placebo-controlled cross-over clinical study.Sleep & breathing = Schlaf & Atmung · 2026Trial
- Trial
- Effect of viloxazine and trazodone in obstructive sleep apnoea: a randomised, placebo-controlled, cross-over study.Thorax · 2025Trial
- Arousal threshold modifies the effect of CPAP on executive function among individuals with obstructive sleep apnoea.The European respiratory journal · 2025Trial
- Soluble cytokine receptor levels in obstructive sleep apnea patients treated with continuous positive airway pressure therapy.Future science OA · 2026Article
- Comment on "soluble cytokine receptor levels in obstructive sleep apnea patients treated with continuous positive airway pressure therapy".Future science OA · 2026Article
- Polysomnographic arousal index and periodic limb movement index in patients undergoing coronary artery bypass grafting: an exploratory case-comparison study.Sleep & breathing = Schlaf & Atmung · 2026Article
- Obstructive sleep apnea in patients with acute myocardial infarction: one-year follow-up study.Sleep & breathing = Schlaf & Atmung · 2026Article
- Objective and subjective adherence to oral appliance therapy in adults with obstructive sleep apnea: pilot data from a one-year longitudinal study.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2026Article
- Heterogeneity of vascular inflammation in obstructive sleep apnea: effects of continuous positive airway pressure therapy.Annals of the American Thoracic Society · 2026Article
- Respiratory Inductance Plethysmography to Quantify Changes in Ventilation in Obstructive Sleep Apnea.IEEE transactions on bio-medical engineering · 2026Article
- Sleep apnoea and its consequences: from animal models to precision medicine.Sleep medicine · 2026Review
- Individualized treatment effects of CPAP on secondary cardiovascular outcomes in non-sleepy obstructive sleep apnea patients.Communications medicine · 2026Article
- Associations Between the Severity of Obstructive Sleep Apnea and Arterial Stiffness Estimated by Pulse Wave Velocity Assessment: A Cross-Sectional Study.Health science reports · 2026Article
- Linking sleep apnea and arthritis in the National Alzheimer Coordinating Center Cohort: A cross-sectional analysis.Medicine · 2026Article
- Sleep Apnea Pathophysiology in Patients with a History of COVID-19.Journal of clinical medicine · 2026Article
- Obstructive sleep apnea contributes to coronary artery disease development and poor prognosis.American journal of translational research · 2026Article
- The impact of obstructive sleep apnea and heart rate on arterial stiffness: results from the Tokyo Sleep Heart Study.Hypertension research : official journal of the Japanese Society of Hypertension · 2025Article
5 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
12 authors at 2 institutions in 4 countries.
Ali AzarbarzinDivision of Sleep and Circadian Disorders, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts.ORCID 0000-0002-4986-4753
Andrey ZinchukPulmonary, Critical Care, and Sleep Medicine, Yale Medicine, Yale University, New Haven, Connecticut.ORCID 0000-0003-0488-9778
Andrew WellmanDivision of Sleep and Circadian Disorders, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts.
Gonzalo LabarcaDivision of Sleep and Circadian Disorders, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts.
Daniel VenaDivision of Sleep and Circadian Disorders, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts.
Laura GellDivision of Sleep and Circadian Disorders, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts.
Ludovico MessineoDivision of Sleep and Circadian Disorders, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts.
David P WhiteDivision of Sleep and Circadian Disorders, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts.
Daniel J GottliebDivision of Sleep and Circadian Disorders, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts.ORCID 0000-0001-8812-8751
Susan RedlineDivision of Sleep and Circadian Disorders, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts.
Yüksel PekerDivision of Sleep and Circadian Disorders, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts.
Scott A SandsDivision of Sleep and Circadian Disorders, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts.
Brigham and Women's Hospital · USYale University · US
Funding
Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9MHARVARD CLINICAL AND TRANSLATIONAL SCIENCE CENTER (UL1)UL1RR025758 · NCRR · HARVARD MEDICAL SCHOOL · PI NADLER, LEE MARSHALL · 2008 to 2011
$91.4MWakefulness and Forebrain Activation by Orexin NeuronsP01HL095491 · NHLBI · BETH ISRAEL DEACONESS MEDICAL CENTER · PI SAPER, CLIFFORD B · 2010 to 2019
$25.1MValidation of a Phenotype Model to Predict Response to Alternative OSA TreatmentsR01HL102321 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI WELLMAN, DAVID ANDREW · 2011 to 2025
$7.3MPhenotypic and Molecular Signatures for Sleep Apnea and Related MorbiditiesR35HL135818 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI REDLINE, SUSAN S. · 2017 to 2023
$7.2MDetermination of the site of pharyngeal collapse in Obstructive Sleep Apnea patients from snoring soundsR01HL128658 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI WELLMAN, DAVID ANDREW · 2016 to 2025
$4.3MA Novel Pharmacological Therapy for Obstructive Sleep ApneaR01HL146697 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI SANDS, SCOTT A · 2019 to 2023
$3.4MPhenotyping Mechanistic Pathways for Adverse Health Outcomes in Sleep ApneaR01HL153874 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI AZARBARZIN, ALI · 2020 to 2024
$3.3MNovel physiologiC prEdictors of Positive Airway Pressure effectiveness: NICE-PAP study.K23HL159259 · NHLBI · YALE UNIVERSITY · PI ZINCHUK, ANDREY · 2021 to 2025
$843kNovel physiologically-driven phenotypes for the prognosis of cardiovascular outcomes in sleep apnea: Toward precision medicine in sleep healthR21HL161766 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI AZARBARZIN, ALI · 2022 to 2023
$279kDeep learning of awake and sleep electrocardiography to identify atrial fibrillation risk in sleep apneaR21HL167126 · NHLBI · UNIVERSITY OF WASHINGTON · PI AKBILGIC, OGUZ, AZARBARZIN, ALI · 2023 to 2024
$202kNCATS NIH HHS UL1 TR001863NCRR NIH HHS UL1 RR025758NHLBI NIH HHS K23 HL159259NHLBI NIH HHS P01 HL095491NHLBI NIH HHS R01 HL102321NHLBI NIH HHS R01 HL128658NHLBI NIH HHS R01 HL146697NHLBI NIH HHS R01 HL153874NHLBI NIH HHS R21 HL161766NHLBI NIH HHS R21 HL167126NHLBI NIH HHS R35 HL135818NIH HHS R01HL153874
Abstract
PubMed holds no abstract for this paper.
Indexed as
Coronary Artery DiseaseDisorders of Excessive SomnolenceSleep Apnea, ObstructiveAdultAgedContinuous Positive Airway PressureFemaleHumansMaleMiddle AgedProspective StudiesSleepinessTreatment Outcomecardiovascularclinical trialheart rate responsesleep apneasleepiness
Identifiers
What OpenQuestion holds
Textmetadata
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.