Evidence map›Paper›PMID 35579440›Full record

ArticleMicrobiology spectrum2022

The EnvZ/OmpR Two-Component System Regulates the Antimicrobial Activity of TAT-RasGAP

Maria Georgieva, Tytti Heinonen, Simone Hargraves, Trestan Pillonel, Christian Widmann, Nicolas Jacquier

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Microbiology spectrum, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.1field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Maria GeorgievaDepartment of Biomedical Sciences, University of Lausannegrid.9851.5, Lausanne, Switzerland.
Tytti HeinonenInstitute of Microbiologygrid.418800.5, University Hospital Center and University of Lausannegrid.9851.5, Lausanne, Switzerland.
Simone HargravesInstitute of Microbiologygrid.418800.5, University Hospital Center and University of Lausannegrid.9851.5, Lausanne, Switzerland.
Trestan PillonelInstitute of Microbiologygrid.418800.5, University Hospital Center and University of Lausannegrid.9851.5, Lausanne, Switzerland.
Christian Widmann *Department of Biomedical Sciences, University of Lausannegrid.9851.5, Lausanne, Switzerland.
Nicolas Jacquier *Institute of Microbiologygrid.418800.5, University Hospital Center and University of Lausannegrid.9851.5, Lausanne, Switzerland.ORCID 0000-0002-1974-8161
University of Lausanne · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The rapid emergence of antibiotic-resistant bacteria poses a serious threat to public health worldwide. Antimicrobial peptides (AMPs) are promising antibiotic alternatives; however, little is known about bacterial mechanisms of AMP resistance and the interplay between AMP resistance and the bacterial response to other antimicrobials. In this study, we identified Escherichia coli mutants resistant to the TAT-RasGAP

Indexed as

Bacterial ProteinsEscherichia coliEscherichia coli ProteinsTrans-ActivatorsAnti-Bacterial AgentsBacterial Outer Membrane ProteinsDrug Collateral SensitivityGTPase-Activating ProteinsMultienzyme ComplexesPeptide FragmentsPorinsras GTPase-Activating ProteinsAnti-Bacterial AgentsBacterial Outer Membrane ProteinsBacterial ProteinsenvZ protein, E coliEscherichia coli ProteinsGTPase-Activating ProteinsMultienzyme Complexesosmolarity response regulator proteinsPeptide FragmentsPorinsras GTPase-Activating ProteinsTAT-RasGAP(317-326)Trans-Activatorsantibiotic resistanceantimicrobial peptideEscherichia coliTAT-RasGAP317-326two-component system

Identifiers

PMID35579440
PMCPMC9241736
OpenAlexW4280492983

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.