Evidence map›Paper›PMID 35579416›Full record

ArticleeLife2022

Typhoid toxin sorting and exocytic transport from

Shu-Jung Chang, Yu-Ting Hsu, Yun Chen, Yen-Yi Lin, Maria Lara-Tejero, Jorge E Galan

Open access · goldAbstract read
In one paragraph

Article in eLife, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.2field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 15 citations in OpenAlex.

  1. Review
  2. Review
  3. Protein-centric mechanisms of typhoidalFrontiers in cellular and infection microbiology · 2026
    Review
  4. Article
  5. Review
  6. Article
  7. Infection biology ofEcoSal Plus · 2024
    Review
  8. Article
  9. Article
  10. Article
  11. The diverse landscape of AB5-type toxins.Engineering microbiology · 2023
    Review
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Shu-Jung ChangDepartment of Microbial Pathogenesis, Yale University School of Medicine, New Haven, United States.ORCID 0000-0002-6037-6339
Yu-Ting HsuGraduate Institute of Microbiology, College of Medicine, National Taiwan University, Taipei, Taiwan.
Yun ChenGraduate Institute of Microbiology, College of Medicine, National Taiwan University, Taipei, Taiwan.
Yen-Yi LinGraduate Institute of Microbiology, College of Medicine, National Taiwan University, Taipei, Taiwan.
Maria Lara-TejeroDepartment of Microbial Pathogenesis, Yale University School of Medicine, New Haven, United States.ORCID 0000-0002-1339-0859
Jorge E GalanDepartment of Microbial Pathogenesis, Yale University School of Medicine, New Haven, United States.ORCID 0000-0002-6531-0355
National Taiwan University · TWYale University · US

Funding

Typhoid Toxin and Salmonella Typhi pathogenesisR01AI114618 · NIAID · YALE UNIVERSITY · PI GALAN, JORGE E · 2014 to 2023
$5.4M
Virulence factors of Salmonella TyphiR01AI079022 · NIAID · YALE UNIVERSITY · PI GALAN, JORGE E · 2008 to 2012
$2.0M
Virulence factors of Salmonella TyphiR56AI079022 · NIAID · YALE UNIVERSITY · PI GALAN, JORGE E · 2014 to 2014
$486k
NIAID NIH HHS R01 AI079022NIAID NIH HHS R01 AI114618NIAID NIH HHS R56 AI079022
6 · The paper itself

Abstract

Typhoid toxin is an essential virulence factor for

Indexed as

ImmunotoxinsTyphoid FeverHumansSalmonellaSalmonella typhiImmunotoxinsbacterial pathogenesisbacterial toxinsexocytosisinfectious diseaseintracellular pathogensmicrobiologyS. enterica serovar typhityphoid fevervesicle transport

Identifiers

PMID35579416
PMCPMC9142146
OpenAlexW4280507357

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.