Trial reportInteractive cardiovascular and thoracic surgery2022
Early postoperative pain after subxiphoid uniportal thoracoscopic major lung resection: a prospective, single- blinded, randomized controlled trial.
Trial report in Interactive cardiovascular and thoracic surgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03331588 (Comparison Study of Post-operative Pain and Quality of Life Between Subxiphoid and Intercostal Vedio-assisted Thoracic Surgery for Radical Lung Cancer Resection), which is not on this map. Cited by 14 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Comparison Study of Post-operative Pain and Quality of Life Between Subxiphoid and Intercostal Vedio-assisted Thoracic Surgery for Radical Lung Cancer Resection
Who cites it
14 citing papers in PubMed, 20 citations in OpenAlex.
- Periareolar approach in video-assisted thoracoscopic surgery for right middle lobectomy: a novel technique.Surgical endoscopy · 2024Trial
- Pain management strategies following thoracic surgery: best practices and innovations.Journal of thoracic disease · 2026Review
- Less pain and earlier recovery after extra-thoracic single-port robotic lung resection: a propensity-matched comparison.Journal of robotic surgery · 2026Article
- Uniportal VATS for anatomical lung resection: 15 years of innovation.Frontiers in surgery · 2026Review
- Feasibility and safety of outside the cage subcostal robotic anatomical lung resections: results of a phase I clinical trial.Journal of thoracic disease · 2025Article
- Article
- Comparison of the efficacy of subxiphoid and intercostal uniportal video-assisted thoracoscopic surgery in patients with early-stage non-small cell lung cancer.Pakistan journal of medical sciences · 2025Article
- Persistent cough after segmental resection, an issue that clinicians need to pay more attention to.Frontiers in oncology · 2025Article
- Effect of sevoflurane combined with intercostal block on postoperative pulmonary function, opioid consumption, and stress response in lung cancer surgery patients.American journal of cancer research · 2025Article
- Application of drainage strategy with bi-pigtail catheters in patients undergoing lobectomy by uniportal video-assisted thoracic surgery.Journal of thoracic disease · 2024Article
- Efficacy of uniportal versus multiportal video-assisted thoracoscopic lobectomy for non-small cell lung cancer: A retrospective analysis.Pakistan journal of medical sciences · 2024Article
- Suction versus non-suction drainage strategy after uniportal thoracoscopic lung surgery: a prospective cohort study.Journal of thoracic disease · 2024Article
- Article
- Experiences of novel cotton device for uniportal video-assisted thoracoscopic surgery: CS Two-Way HandleJournal of thoracic disease · 2023Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
Abstract
objectivesPreoperative selection bias led to the inability to generalize the proposed benefit of subxiphoid uniportal video-assisted thoracoscopic surgery (SVATS) as having less postoperative pain than uniportal intercostal VATS. So, we conducted this prospective, single-blinded, randomized controlled trial to investigate the hypothesis that SVATS may have less early postoperative pain than UVATS in patients who undergo major lung resection for early-stage lung cancer. METHODSA TOTAL OF: 262 patients were randomly allocated between 2 groups (each with 131 patients), the first being the UVATS group and the second being the SVATS group. The values indicated on the numerical rating scale (NRS) of pain were collected at 24 h and 48 h during rest and during coughing. In addition, different perioperative variables were analysed and compared between the 2 groups.
resultsMultiple linear regression analysis showed that the type of surgical approach was a significant predictor of the postoperative NRS values. The postoperative NRS pain values were significantly lower in the SVATS group after 24 h during rest and coughing and after 48 h during coughing. Postoperatively, patients in the SVATS group got out of bed significantly earlier [16.37 (2.54) vs 18.05 (3.29) h, p < 0.001]. The SVATS group showed a significantly higher rate of intraoperative arrhythmia [20 (15.3%) vs 3 (2.3%) patients, p = 0.03].
conclusionsSVATS major pulmonary resection in early-stage lung cancer is associated with less early postoperative pain than the UVATS approach. Operating on patients with cardiac problems using the SVATS approach is still a limiting factor for randomization due to the potential compression on the heart with resulting arrhythmia. CLINICAL
trial registrationThe trial was registered under clinical trials.gov Identifier: NCT03331588. https://clinicaltrials.gov/ct2/show/NCT03331588.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.