Evidence map›Paper›PMID 35579189›Full record

ArticleLab on a chip2022

Microfluidic harvesting of breast cancer tumor spheroid-derived extracellular vesicles from immobilized microgels for single-vesicle analysis.

Xilal Y Rima, Jingjing Zhang, Luong T H Nguyen, Aaron Rajasuriyar, Min Jin Yoon, Chi-Ling Chiang, Nicole Walters, Kwang Joo Kwak, L James Lee, Eduardo Reátegui

Open access · greenAbstract read
In one paragraph

Article in Lab on a chip, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Xilal Y RimaWilliam G. Lowrie Department of Chemical and Biomolecular Engineering, The Ohio State University, Columbus, OH 43210, USA. reategui.8@osu.edu.ORCID 0000-0001-5633-5887
Jingjing ZhangWilliam G. Lowrie Department of Chemical and Biomolecular Engineering, The Ohio State University, Columbus, OH 43210, USA. reategui.8@osu.edu.
Luong T H NguyenWilliam G. Lowrie Department of Chemical and Biomolecular Engineering, The Ohio State University, Columbus, OH 43210, USA. reategui.8@osu.edu.
Aaron RajasuriyarWilliam G. Lowrie Department of Chemical and Biomolecular Engineering, The Ohio State University, Columbus, OH 43210, USA. reategui.8@osu.edu.
Min Jin YoonWilliam G. Lowrie Department of Chemical and Biomolecular Engineering, The Ohio State University, Columbus, OH 43210, USA. reategui.8@osu.edu.
Chi-Ling ChiangWilliam G. Lowrie Department of Chemical and Biomolecular Engineering, The Ohio State University, Columbus, OH 43210, USA. reategui.8@osu.edu.
Nicole WaltersWilliam G. Lowrie Department of Chemical and Biomolecular Engineering, The Ohio State University, Columbus, OH 43210, USA. reategui.8@osu.edu.
Kwang Joo KwakSpot Biosystems Ltd., Palo Alto, CA 94301, USA.
L James LeeWilliam G. Lowrie Department of Chemical and Biomolecular Engineering, The Ohio State University, Columbus, OH 43210, USA. reategui.8@osu.edu.
Eduardo ReáteguiWilliam G. Lowrie Department of Chemical and Biomolecular Engineering, The Ohio State University, Columbus, OH 43210, USA. reategui.8@osu.edu.ORCID 0000-0002-8271-8205
The Ohio State University · US

Funding

Multi-parametric Integrated Molecular Detection of SARS-CoV-2 from Biofluids by Adapting Single Extracellular Vesicle Characterization TechnologiesU18TR003807 · NCATS · OHIO STATE UNIVERSITY · PI LEE, INYOUL, LEE, LY JAMES · 2021 to 2022
$1.8M
Microfluidics Array Based Sorting, Isolation, and RNA Analysis in Single Extracellular V csiclesUH3TR002884 · NCATS · OHIO STATE UNIVERSITY · PI KIM, BETTY, REATEGUI, EDUARDO · 2021 to 2022
$1.7M
Microfluidics Array Based Sorting, Isolation, and RNA Analysis in Single Extracellular V csiclesUG3TR002884 · NCATS · OHIO STATE UNIVERSITY · PI KIM, BETTY, REATEGUI, EDUARDO · 2019 to 2020
$822k
NCATS NIH HHS U18 TR003807NCATS NIH HHS UG3 TR002884NCATS NIH HHS UH3 TR002884
6 · The paper itself

Abstract

Investigating cellular and vesicular heterogeneity in breast cancer remains a challenge, which encourages the development of controllable

Indexed as

Breast NeoplasmsExtracellular VesiclesMicrogelsCell Culture TechniquesFemaleHumansMicrofluidicsTumor MicroenvironmentMicrogels

Identifiers

PMID35579189
PMCPMC9383696
OpenAlexW4280654206

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.