Evidence map›Paper›PMID 35579056›Full record

ArticleEuropean journal of clinical investigation2022

Lifestyle changes and kidney function: A 10-year follow-up study in patients with manifest cardiovascular disease.

Helena Bleken Østergaard, Imre Demirhan, Jan Westerink, Marianne C Verhaar, Folkert W Asselbergs, Gert J de Borst, L Jaap Kappelle, Frank L J Visseren, Joep van der Leeuw, UCC-SMART studygroup

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Article in European journal of clinical investigation, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Helena Bleken ØstergaardDepartment of Vascular Medicine, University Medical Center Utrecht, Utrecht, the Netherlands.
Imre DemirhanDepartment of Vascular Medicine, University Medical Center Utrecht, Utrecht, the Netherlands.
Jan WesterinkDepartment of Vascular Medicine, University Medical Center Utrecht, Utrecht, the Netherlands.
Marianne C VerhaarDepartment of Nephrology and Hypertension, University Medical Center Utrecht, Utrecht, the Netherlands.
Folkert W AsselbergsDivision Heart & Lungs, Department of Cardiology, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands.
Gert J de BorstDepartment of Vascular Surgery, University Medical Center Utrecht, Utrecht, the Netherlands.
L Jaap KappelleDepartment of Neurology, University Medical Center Utrecht, Utrecht, the Netherlands.
Frank L J VisserenDepartment of Vascular Medicine, University Medical Center Utrecht, Utrecht, the Netherlands.ORCID https://orcid.org/0000-0003-3951-5223
Joep van der LeeuwDepartment of Nephrology and Hypertension, University Medical Center Utrecht, Utrecht, the Netherlands.
UCC-SMART studygroup

Funding

UCL Hospitals NIHR Biomedical Research CentreUniversity Medical Center Utrecht
6 · The paper itself

Abstract

backgroundPatients with cardiovascular disease (CVD) are at higher risk of kidney function decline. The current study aimed to examine the association of lifestyle changes with kidney function decline in patients with manifest CVD.

methodsA total of 2260 patients from the Utrecht Cardiovascular Cohort-Second Manifestations of ARTerial disease cohort with manifest CVD who returned for a follow-up visit after a median of 9.9 years were included. The relation between change in lifestyle factors (smoking, alcohol consumption, physical activity and obesity) and change in kidney function (eGFR and uACR) was assessed using linear regression models.

resultsAn increase in body mass index (β -2.81; 95% CI -3.98; -1.63 per 5 kg/m

conclusionsIn patients with CVD, continuing smoking, recent smoking cessation and an increase in obesity markers were related to a steeper kidney function decline. Although no definite conclusions from this study can be drawn, the results support the importance of encouraging weight loss and smoking cessation in high-risk patients as a means of slowing down kidney function decline.

Indexed as

Cardiovascular DiseasesFollow-Up StudiesHumansKidneyLife StyleMaleObesityRisk Factorscardiovascular diseasekidney function declinelifestyle factors

Identifiers

PMID35579056
PMCPMC9540114

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.