Evidence map›Paper›PMID 35578690›Full record

ArticleDisease markers2022

Iodine-125 Seeds Inhibit Carcinogenesis of Hepatocellular Carcinoma Cells by Suppressing Epithelial-Mesenchymal Transition via TGF-

Chongshuang Yang, Yunhua Xiao, Yexiang Du, Junru Xiong, Liangyu Deng, Qinghua Liang, Jing Yuan, Chuang He, Fengtian He, Xuequan Huang

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Disease markers, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Chongshuang YangTreatment Center of Minimally Invasive Intervention and Radioactive Particles, First Affiliated Hospital of the Army Medical University, Chongqing, China.ORCID https://orcid.org/0000-0003-3621-4548
Yunhua XiaoTreatment Center of Minimally Invasive Intervention and Radioactive Particles, First Affiliated Hospital of the Army Medical University, Chongqing, China.
Yexiang DuDepartment of Digestive Medicine, The Second Affiliated Hospital of Army Medical University, Army Medical University, Chongqing, China.
Junru XiongTreatment Center of Minimally Invasive Intervention and Radioactive Particles, First Affiliated Hospital of the Army Medical University, Chongqing, China.
Liangyu DengTreatment Center of Minimally Invasive Intervention and Radioactive Particles, First Affiliated Hospital of the Army Medical University, Chongqing, China.
Qinghua LiangTreatment Center of Minimally Invasive Intervention and Radioactive Particles, First Affiliated Hospital of the Army Medical University, Chongqing, China.
Jing YuanDepartment of Radiology, The Third Affiliated Hospital of Army Medical University, Army Medical University, Chongqing, China.
Chuang HeTreatment Center of Minimally Invasive Intervention and Radioactive Particles, First Affiliated Hospital of the Army Medical University, Chongqing, China.
Fengtian HeDepartment of Biochemistry and Molecular Biology, College of Basic Medical Sciences, Army Medical University, Chongqing, China.ORCID https://orcid.org/0000-0001-7904-7490
Xuequan HuangTreatment Center of Minimally Invasive Intervention and Radioactive Particles, First Affiliated Hospital of the Army Medical University, Chongqing, China.ORCID https://orcid.org/0000-0002-0807-5563
Army Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To investigate the radioactive iodine-125 (I-125) seed on migrating and invading of hepatocellular carcinoma (HCC) cells and its mechanism, the irradiation of PLC and Huh7 cells was carried out with I-125 seeds in vitro. Cell counting kit 8 assay was employed to measure cell viability. Cell migration was evaluated by using wound-healing assay. Cell invasion was detected by Transwell assay; RT-PCR and Western blot were used for the detection of the mRNA and proteins of TGF-

Indexed as

Carcinoma, HepatocellularLiver NeoplasmsThyroid NeoplasmsCarcinogenesisCell Line, TumorCell MovementEpithelial-Mesenchymal TransitionHumansIodine RadioisotopesRNA, MessengerSignal TransductionTransforming Growth Factor beta1Iodine-125Iodine RadioisotopesRNA, MessengerTransforming Growth Factor beta1

Identifiers

PMID35578690
PMCPMC9107354
OpenAlexW4229023012

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.