ArticleJournal of biomedical optics2022
Unsupervised super-resolution reconstruction of hyperspectral histology images for whole-slide imaging.
Article in Journal of biomedical optics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 22 papers, 1 of them a synthesis that pooled it.
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Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Medical hyperspectral imaging: an updated review of technology advancements and biomedical applications.Journal of biomedical optics · 2026Pooled it
- Polarized hyperspectral and polarized light microscopic imaging for enhanced visualization of white blood cells.Journal of biomedical optics · 2026Article
- Development and validation of a high-resolution hyperspectral imaging system for the retina.Journal of biomedical optics · 2026Article
- Image Feature Fusion of Hyperspectral Imaging and MRI for Automated Subtype Classification and Grading of Adult Diffuse Gliomas According to the 2021 WHO Criteria.Diagnostics (Basel, Switzerland) · 2026Article
- Autofluorescence and deep learning in early disease detection: biological foundations, clinical applications, and future directions.Frontiers in artificial intelligence · 2026Review
- Label-free optical microscopy with artificial intelligence: a new paradigm in pathology.Biophotonics discovery · 2025Review
- A spatial-spectral vision transformer model for head and neck cancer detection with hyperspectral, RGB, and synthesized RGB histologic images.Proceedings of SPIE--the International Society for Optical Engineering · 2025Article
- Optimization of Transfer Learning of Foundation Models for Hyperspectral Histologic Imaging.Proceedings of SPIE--the International Society for Optical Engineering · 2025Article
- A Dual-Camera High-Resolution Hyperspectral Imaging System for the Retina.Proceedings of SPIE--the International Society for Optical Engineering · 2025Article
- An automatic processing framework for hyperspectral histologic images and benchmark dataset.Proceedings of SPIE--the International Society for Optical Engineering · 2025Article
- HcGAN: Harmonic conditional generative adversarial network for efficiently generating high-quality IHC images from H&E.Heliyon · 2024Article
- Detection and margin assessment of thyroid carcinoma with microscopic hyperspectral imaging using transformer networks.Journal of biomedical optics · 2024Article
- Spatial and Spectral Reconstruction of Breast Lumpectomy Hyperspectral Images.Sensors (Basel, Switzerland) · 2024Article
- Dual-camera laparoscopic imaging with super-resolution reconstruction for intraoperative hyperspectral image guidance.Proceedings of SPIE--the International Society for Optical Engineering · 2024Article
- Nerve Detection and Visualization Using Hyperspectral Imaging for Surgical Guidance.Proceedings of SPIE--the International Society for Optical Engineering · 2024Article
- A hyperspectral surgical microscope with super-resolution reconstruction for intraoperative image guidance.Proceedings of SPIE--the International Society for Optical Engineering · 2024Article
- Polarized hyperspectral microscopic imaging system for enhancing the visualization of collagen fibers and head and neck squamous cell carcinoma.Journal of biomedical optics · 2024Article
- Extended Depth of Field Imaging for Mosaic Hyperspectral Images.Proceedings of SPIE--the International Society for Optical Engineering · 2023Article
- A Video Transformer Network for Thyroid Cancer Detection on Hyperspectral Histologic Images.Proceedings of SPIE--the International Society for Optical Engineering · 2023Article
- Conditional Generative Adversarial Network (cGAN) for Synthesis of Digital Histologic Images from Hyperspectral Images.Proceedings of SPIE--the International Society for Optical Engineering · 2023Article
Corrections and comments
- Erratum issued
Authors and funding
5 authors.
Funding
Abstract
significanceHyperspectral imaging (HSI) provides rich spectral information for improved histopathological cancer detection. However, acquiring high-resolution HSI data for whole-slide imaging (WSI) can be time-consuming and requires a huge amount of storage space.
aimWSI using a color camera can be achieved with fast speed, high image resolution, and excellent image quality due to the established techniques. We aim to develop an RGB-guided unsupervised hyperspectral super-resolution reconstruction method that is hypothesized to improve image quality while maintaining the spectral characteristics. APPROACH: High-resolution hyperspectral images of 32 histologic slides were obtained via automated WSI. High-resolution RGB histology images were registered to the hyperspectral images for RGB guidance. An unsupervised super-resolution network was trained to take the downsampled low-resolution hyperspectral patches (LR-HSI) and high-resolution RGB patches (HR-RGB) as inputs to reconstruct high-resolution hyperspectral patches (HR-HSI). Then, an Inception-based network was trained with the HR-RGB, original HR-HSI, and generated HR-HSI, respectively, for whole-slide histopathological cancer detection.
resultsOur super-resolution reconstruction network generated high-resolution hyperspectral images with well-maintained spectral characteristics and improved image quality. Image classification using the original hyperspectral data outperformed RGB because of the extra spectral information. The generated hyperspectral image patches further improved the results.
conclusionsThe proposed method potentially reduces image acquisition time, saves storage space without compromising image quality, and improves the image classification performance.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.