Evidence map›Paper›PMID 35578377›Full record

ArticleVeterinary clinical pathology2022

Severe hyperferremia and hyperferritinemia in a dog with precursor-directed immune-mediated anemia.

Kristin M Zersen, Carly W Gregory, Christina M Jeffries, Christine Olver

Open access · hybridAbstract readCase Reports
In one paragraph

Article in Veterinary clinical pathology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Kristin M ZersenDepartment of Clinical Sciences, Colorado State University, Fort Collins, CO, USA.ORCID https://orcid.org/0000-0003-0327-8537
Carly W GregoryDepartment of Clinical Sciences, Colorado State University, Fort Collins, CO, USA.
Christina M JeffriesDepartment of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, Colorado, USA.ORCID https://orcid.org/0000-0002-6899-8255
Christine OlverDepartment of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, Colorado, USA.ORCID https://orcid.org/0000-0002-9937-2706
Colorado State University · US

Funding

Colorado State University
6 · The paper itself

Abstract

A 4-year-old dog was evaluated at the Colorado State University Veterinary Teaching Hospital for lethargy and hyporexia of 24 hours duration. On presentation, she had a marked normocytic, normochromic, nonregenerative anemia (HCT 14%; RI 40-55). Her serum iron concentration (1651 μg/dL; RI 73-245) and serum ferritin concentration (1337 ng/mL; RI 89-489) were markedly elevated. Bone marrow aspirate and core biopsy were consistent with a diagnosis of precursor-directed immune-mediate anemia. To the authors' knowledge, these are the highest reported serum iron and ferritin concentrations in a patient with precursor-directed immune-mediate anemia. The iron concentration improved significantly after treatment, supporting the theory that the hyperferremia was due to hemolysis and ineffective erythropoiesis.

Indexed as

AnemiaDog DiseasesHyperferritinemiaAnimalsDogsFemaleFerritinsHospitals, AnimalHospitals, TeachingIronFerritinsIronferritinironnonregenerative anemia

Identifiers

PMID35578377
PMCPMC10084362
OpenAlexW4280490997

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.