Evidence map›Paper›PMID 35578314›Full record

ArticleBMC neurology2022

Bromisoval-induced bromism with status epilepticus mimicking Wernicke's encephalopathy: report of two cases.

Masahiro Biyajima, Shunichi Satoh, Takahiro Morikawa, Yuki Morita, Rie Watanabe, Daisuke Matsui, Masataka Konno, Nobutoshi Morimoto, Yuichi Yatsu, Akihito Hirasaki and 1 more

Open access · goldAbstract readCase Reports
In one paragraph

Article in BMC neurology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Masahiro BiyajimaDepartment of Neurology, Nagano Red Cross Hospital, 5-22-1, Wakasato, Nagano, 380-8582, Japan. biyajima@shinshu-u.ac.jp.ORCID http://orcid.org/0000-0002-7257-0796
Shunichi SatohDepartment of Neurology, Nagano Red Cross Hospital, 5-22-1, Wakasato, Nagano, 380-8582, Japan.
Takahiro MorikawaDepartment of Neurology, Nagano Red Cross Hospital, 5-22-1, Wakasato, Nagano, 380-8582, Japan.
Yuki MoritaDepartment of Neurology, Nagano Red Cross Hospital, 5-22-1, Wakasato, Nagano, 380-8582, Japan.
Rie WatanabeDepartment of Neurology, Nagano Red Cross Hospital, 5-22-1, Wakasato, Nagano, 380-8582, Japan.
Daisuke MatsuiDepartment of Nephrology, Nagano Red Cross Hospital, Nagano, Japan.
Masataka KonnoDepartment of Psychiatry, Nagano Red Cross Hospital, Nagano, Japan.
Nobutoshi MorimotoDepartment of Neurology, Kagawa Prefectural Central Hospital, Takamatsu, Kagawa, Japan.
Yuichi YatsuDepartment of Anesthesiology, Kagawa Prefectural Central Hospital, Takamatsu, Kagawa, Japan.
Akihito HirasakiDepartment of Anesthesiology, Kagawa Prefectural Central Hospital, Takamatsu, Kagawa, Japan.
Hiroyuki YahikozawaDepartment of Neurology, Nagano Red Cross Hospital, 5-22-1, Wakasato, Nagano, 380-8582, Japan.
Nagano Red Cross Hospital · JPKagawa Prefectural Central Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBromine compounds are used in several drugs, including over-the-counter drugs. They sometimes cause intoxication known as bromism. Although the acute neurological symptoms and sequelae of bromism vary, few reports have mentioned acute encephalopathy. CASE PRESENTATION: We report two cases of bromisoval-induced bromism with status epilepticus. Presence of pseudohyperchloremia and history of over-the-counter medication use guided the diagnosis. In the acute phase, our patients showed bilateral medial thalamic lesions on magnetic resonance imaging. The imaging findings were similar to those of Wernicke's encephalopathy. Although these findings improved in the chronic phase, neuropsychiatric sequelae, such as confabulation and amnesia, occurred.

conclusionBromism can cause acute encephalopathy, and it is important to differentiate it from Wernicke-Korsakoff syndrome.

Indexed as

BromisovalumKorsakoff SyndromeStatus EpilepticusWernicke EncephalopathyHumansMemory DisordersBromisovalumBromismBromisovalBromovalerylureaKorsakoff’s syndromeStatus epilepticusWernicke’s encephalopathy

Identifiers

PMID35578314
PMCPMC9109394
OpenAlexW4280517756

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.