ReviewAnnals of clinical microbiology and antimicrobials2022
A fatal case of disseminated nocardiosis due to Nocardia otitidiscaviarum resistant to trimethoprim-sulfamethoxazole: case report and literature review.
Review in Annals of clinical microbiology and antimicrobials, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
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Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.
- Outcomes and treatment for disseminated nocardiosis caused by Nocardia otitidiscaviarum: a systematic review.BMC infectious diseases · 2026Pooled it
- Article
- Pulmonary Nocardia otitidiscaviarum in immunocompetent individuals: a case series and literature review.BMC infectious diseases · 2026Review
- Essential fatty acids disrupt the mycolic acid-rich cell envelope of clinicalFrontiers in cellular and infection microbiology · 2026Article
- Linezolid and Meropenem for Nocardia otitidiscaviarum Actinomycetoma, India.Emerging infectious diseases · 2025Article
- Case Report: Nanopore Sequencing-Based Detection of Pulmonary Nocardiosis Caused by Nocardia Otitidiscaviarum in an Immunocompetent Patient.Infection and drug resistance · 2025Article
- Genomic and phenotypic characterization of antimicrobial resistance in clinicalFrontiers in cellular and infection microbiology · 2025Article
- The first known case of Nocardia wallacei infection in Cyprus.GMS hygiene and infection control · 2025Article
- First Documented Case of Pneumonia withInfection and drug resistance · 2025Article
- Case Report: A case ofFrontiers in medicine · 2025Article
- Article
- Recurrent pulmonary nocardiosis due to Nocardia Otitidiscaviarum in a patient with isolated CD4 lymphocytopenia: a case report.BMC infectious diseases · 2024Article
- Cavitary pneumonia and empyema thoracis caused by multidrug resistant Nocardia otitidiscaviarum in an elderly patient.Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia · 2024Article
- Article
- Weathering the storm: diagnosis and treatment of a life-threatening disseminatedFrontiers in cellular and infection microbiology · 2024Article
- Article
- Article
- Large mediastinal mass diagnosed as Nocardia infection by endobronchial ultrasound-guided transbronchial needle aspiration in a ceramic worker: A case report.Frontiers in surgery · 2022Article
Corrections and comments
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Authors and funding
9 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDisseminated nocardiosis still causes significant morbidity and mortality and is often caused by Nocardia asteroides, N. basiliensis, and N. farcinica and are often treated with trimethoprim-sulfamethoxazole (TMP-SMX). Nocardia otitidiscaviarum (N. otitidiscaviarum) rarely causes disseminated disease and resistance to TMP-SMX is even more rare. CASE PRESENTATION: A 37-year-old woman with metastatic breast cancer and right ear deafness with recent occupational gardening and manipulating soil, presented to the hospital with first time seizure and multiple skin nodules. Magnetic resonance imaging (MRI) showed ring enhancing lesions, biopsy of the skin and brain lesions grew N. otitidiscaviarum. She was empirically treated with TMP-SMX and Imipenem-Cilastatin, however, almost three weeks into therapy, susceptibility results revealed it to be resistant to both antimicrobials, she was subsequently changed to Amikacin, Linezolid, Moxifloxacin, and Doxycycline but ultimately died.
conclusionsThis case report highlights the importance of suspecting a rare Nocardia species in patients at risk with proper occupational exposure, moreover, TMP-SMX resistance should be suspected with lack of clinical response, this may have important implications on clinical practice when facing similar infections.
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