Evidence map›Paper›PMID 35578278›Full record

ArticleBMC medical informatics and decision making2022

Predicting acute kidney injury following open partial nephrectomy treatment using SAT-pruned explainable machine learning model.

Teddy Lazebnik, Zaher Bahouth, Svetlana Bunimovich-Mendrazitsky, Sarel Halachmi

Open access · goldAbstract readValidation Study
In one paragraph

Article in BMC medical informatics and decision making, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
3.9field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Teddy Lazebnik *Department of Cancer Biology, Cancer Institute, University College London, London, UK. t.lazebnik@ucl.ac.uk.ORCID 0000-0002-7851-8147
Zaher Bahouth *Department of Urology, Bnai Zion Medical Center, Haifa, Israel.
Svetlana Bunimovich-MendrazitskyDepartment of Mathematics, Ariel University, Ariel, Israel.
Sarel HalachmiDepartment of Urology, Bnai Zion Medical Center, Haifa, Israel.
Bnai Zion Medical Center · ILAriel University · ILCancer Research UK · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundOne of the most prevalent complications of Partial Nephrectomy (PN) is Acute Kidney Injury (AKI), which could have a negative impact on subsequent renal function and occurs in up to 24.3% of patients undergoing PN. The aim of this study was to predict the occurrence of AKI following PN using preoperative parameters by applying machine learning algorithms.

methodsWe included all adult patients (n = 723) who underwent open PN in our department since 1995 and on whom we have data on the pre-operative renal function. We developed a random forest (RF) model with Boolean satisfaction-based pruned decision trees for binary classification (AKI or non-AKI). Hyper-parameter grid search was performed to optimize the model's performance. Fivefold cross-validation was applied to evaluate the model. We implemented a RF model with greedy feature selection to binary classify AKI and non-AKI cases based on pre-operative data.

resultsThe best model obtained a 0.69 precision and 0.69 recall in classifying the AKI and non-AKI groups on average (k = 5). In addition, the model's probability to correctly classify a new prediction is 0.75. The proposed model is available as an online calculator.

conclusionsOur model predicts the occurrence of AKI following open PN with (75%) accuracy. We plan to externally validate this model and modify it to minimally-invasive PN.

Indexed as

Acute Kidney InjuryAdultAlgorithmsDecision TreesHumansMachine LearningNephrectomyPostoperative ComplicationsAKI predictionPN treatment complication predictionSAT pruned random forest

Identifiers

PMID35578278
PMCPMC9112450
OpenAlexW4280512214

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.