ArticleAbdominal radiology (New York)2022
Pre-operative magnetic resonance imaging can predict prostate cancer with risk for positive surgical margins.
Article in Abdominal radiology (New York), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 24 citations in OpenAlex.
- An interpretable nomogram for positive surgical margin risk after laparoscopic and robot-assisted radical prostatectomy: a single-centre development and internal validation study.Journal of robotic surgery · 2026Article
- Article
- Contemporary Evidence for Optimization of Robotic Radical Prostatectomy Outcomes Using Advanced Imaging Techniques.Journal of clinical medicine · 2026Review
- Exploring the use of preoperative MRI for assessing the anatomical location of positive surgical margin at robot-assisted radical prostatectomy (RARP).World journal of urology · 2026Article
- Non-Small Cell Lung Cancer Patients With Tumors ≤ 2 Cm Are Suitable for Wedge Resection or Segmentectomy: A Real-World Study.Thoracic cancer · 2026Article
- Preoperative MRI-based predictive model for biochemical recurrence following radical prostatectomy.Abdominal radiology (New York) · 2025Article
- Association of surgical margin positivity with preoperative mpMRI-identified index lesions in radical prostatectomy A retrospective study.Canadian Urological Association journal = Journal de l'Association des urologues du Canada · 2025Article
- Lesion-based grading system using clinicopathological and MRI features for predicting positive surgical margins in prostate cancer.Abdominal radiology (New York) · 2025Article
- Bicenter validation of a risk model for the preoperative prediction of extraprostatic extension of localized prostate cancer combining clinical and multiparametric MRI parameters.World journal of urology · 2024Article
- Development of preoperative nomograms to predict the risk of overall and multifocal positive surgical margin after radical prostatectomy.Cancer imaging : the official publication of the International Cancer Imaging Society · 2024Article
- Prostate Cancer Local Staging with Magnetic Resonance Imaging.Radiologic clinics of North America · 2024Review
- MRI characteristics and oncological follow-up of patients with ISUP grade group 4 or 5 prostate cancer.Abdominal radiology (New York) · 2024Article
- An MRI-based grading system for preoperative risk estimation of positive surgical margin after radical prostatectomy.Insights into imaging · 2023Article
- Quantitative Dynamic Contrast-Enhanced Magnetic Resonance Parameters Could Predict International Society of Urological Pathology Risk Groups of Prostate Cancers on Radical Prostatectomy.Life (Basel, Switzerland) · 2023Article
- The Diagnostic Performance of Tumor Stage on MRI for Predicting Prostate Cancer-Positive Surgical Margins: A Systematic Review and Meta-Analysis.Diagnostics (Basel, Switzerland) · 2023Review
- Multiparametric Magnetic Resonance Imaging-based Prostate Specific Antigen Density and PI-RADSv2 score help identify Apical Prostate Cancer.Journal of Cancer · 2023Article
- Value of three-dimensional visualization of preoperative prostatic magnetic resonance imaging based on measurements of anatomical structures in predicting positive surgical margin after radical prostatectomy.Frontiers in endocrinology · 2023Article
- Multiparametric MRI-based nomograms in predicting positive surgical margins of prostate cancer after laparoscopic radical prostatectomy.Frontiers in oncology · 2022Article
- Less qualitative multiparametric magnetic resonance imaging in prostate cancer can underestimate extraprostatic extension in higher grade tumors.International braz j urol : official journal of the Brazilian Society of UrologyArticle
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Authors and funding
11 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeAnalysis of patients with pre-operative 3 T multiparametric prostate MRI (mpMRI) to determine reliable MRI-based risk predictors of patients at risk for positive surgical margins (PSM) in robotic assisted radical prostatectomy (RPE).
methodsConsecutive patients with 3 T mpMRI and subsequent RPE from 01/2015 to 12/2018 were retrospectively included. Patients were compared regarding clinical and MRI related parameters such as length of capsular tumor contact (LCC) and distance to the membranous urethra (UD).
resultsForty-nine of 179 patients (27%) had PSM in 70 different localizations, with the majority located at the capsule (57%, 40/70), mostly apical and/or posterior. The second most often PSM occurred at the apical urethra (22%, 15/70). PCA was visible on mpMRI at the localization of PSM in 93% at the capsule and in 80% at the urethra. PSA, PI-RADS classification, extraprostatic extension (EPE), and seminal vesicles infiltration (SVI) on MRI were significantly higher / more frequent in patients with PSM. LCC (AUC 0.710), EPE (AUC 0.693), and UD (1-AUC 0.673) predicted PSM (overall). An UD of ≤ 3.5 mm showed the highest accuracy of 95% (J = 0.946) for PSM at the urethra and a LCC of ≥ 22.5 mm with 77% (J = 0.378) for PSM at the capsule.
conclusionPSM occurred mostly in the apex and/or posteriorly at the capsule or at the apical urethra. LCC was the best MRI predictor for PSM at the capsule and UD for tumors with PSM at the apical urethra. Using these MRI parameters readers might pre-operatively determine PCA localizations at risk for PSM.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.