ArticleScientific reports2022
Effect of vitrectomy with silicone oil tamponade and internal limiting membrane peeling on eyes with proliferative diabetic retinopathy.
Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed, 8 citations in OpenAlex.
- Replacing the vitreous body with hydrogels: Rationale and strategies.Progress in retinal and eye research · 2025Review
- Effectiveness and safety of early lens extraction during par plana vitrectomy for proliferative diabetes retinopathy with mild cataract: a randomized clinical trial.International journal of ophthalmology · 2024Article
- Vitreous Substitutes from Bench to the Operating Room in a Translational Approach: Review and Future Endeavors in Vitreoretinal Surgery.International journal of molecular sciences · 2023Review
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We investigated the combined effect of silicone tamponade and the internal limiting membrane (ILM) peeling and investigated whether timing of peeling of the ILM affects the outcomes of vitrectomy with silicone oil tamponade in eyes with proliferative diabetic retinopathy (PDR). Here, we examined 63 eyes (58 patients) with PDR, which underwent vitrectomy with silicone oil tamponade and stepwise removal of silicone oil. ILM peeling was performed just before oil injection (group 1; 33 eyes, 30 patients) or after oil removal (group 2; 30 eyes, 28 patients). Visual acuity and retinal and choroidal thicknesses were compared between the groups. Thinning of the inner retina, including the ganglion cell-inner plexiform layer and macular retinal nerve fiber layer, was evident at 1 year after surgery in both groups. Thinning of the total retina (P = 0.019) and inner retina (P = 0.008) was significantly correlated with final visual acuity. There was no considerable between-group difference observed in final visual acuity, intraocular pressure, or retinal or choroidal thickness at 1 year after surgery. The incidence of epiretinal membrane was higher during silicone endo-tamponade in group 2 (P = 0.033). Visual recovery and macular configuration in eyes with PDR are not affected by whether the ILM is peeled before or after silicone oil tamponade.
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