Observational studyThe British journal of general practice : the journal of the Royal College of General Practitioners2022
Characterisation of type 2 diabetes subgroups and their association with ethnicity and clinical outcomes: a UK real-world data study using the East London Database.
Observational study in The British journal of general practice : the journal of the Royal College of General Practitioners, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 2 of them syntheses that pooled it.
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Who cites it
8 citing papers in PubMed, 2 syntheses or guidelines pooled it, 4 citations in OpenAlex.
- The Prevalence and Progression of Microvascular Complications and the Interaction With Ethnicity and Socioeconomic Status in People With Type 2 Diabetes: A Systematic Review and Meta-Analysis.Journal of diabetes research · 2025Pooled it
- Ethnic differences between Asians and non-Asians in clustering-based phenotype classification of adult-onset diabetes mellitus: A systematic narrative review.Primary care diabetes · 2022Pooled it
- A four-year retrospective surgical case series examining postoperative complications following Removal of Silicone Oil (ROSO) scored using the Complications of Retinal Detachment Surgery (CORDS) severity classification tool.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026Article
- Clinical phenotypes of type 2 diabetes and their association with microvascular complications in primary care: a cluster analysis.BMC primary care · 2026Article
- Patterns of complication burden in people with diabetes: a latent class analysis approach.Acta diabetologica · 2026Article
- Ethnic differences in the comparative effectiveness of second-line type 2 diabetes medications in preventing cardiovascular disease.Diabetes, obesity & metabolism · 2026Article
- Ethnic differences in CKD progression among people with type 2 diabetes and rapid eGFR decline: A secondary data analysis.BMC nephrology · 2025Article
- Whole-genome sequencing study to identify candidate markers indicating susceptibility to type 2 diabetes in Bama miniature pigs.Animal models and experimental medicine · 2023Article
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
backgroundSubgroups of type 2 diabetes (T2DM) have been well characterised in experimental studies. It is unclear, however, whether the same approaches can be used to characterise T2DM subgroups in UK primary care populations and their associations with clinical outcomes.
aimTo derive T2DM subgroups using primary care data from a multi-ethnic population, evaluate associations with glycaemic control, treatment initiation, and vascular outcomes, and to understand how these vary by ethnicity. DESIGN AND
settingAn observational cohort study in the East London Primary Care Database from 2008 to 2018.
methodLatent-class analysis using age, sex, glycated haemoglobin, and body mass index at diagnosis was used to derive T2DM subgroups in white, South Asian, and black groups. Time to treatment initiation and vascular outcomes were estimated using multivariable Cox-proportional hazards regression.
resultsIn total, 31 931 adults with T2DM were included: 47% South Asian (
conclusionClinically useful T2DM subgroups, identified at diagnosis, can be generated in routine real-world multi-ethnic populations, and may offer a pragmatic means to develop stratified primary care pathways and improve healthcare resource allocation.
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