Evidence map›Paper›PMID 35577469›Full record

ArticleBMJ open2022

Telehealth cancer-related fatigue clinic model for cancer survivors: a pilot randomised controlled trial protocol (the T-CRF trial).

Rahul Ladwa, Elizabeth P Pinkham, Laisa Teleni, Brigid Hanley, Gemma Lock, Jodie Nixon, Oluwaseyifunmi Andi Agbejule, Fiona Crawford-Williams, Lee Jones, Mark B Pinkham and 7 more

Abstract readClinical Trial Protocol
In one paragraph

Article in BMJ open, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Guideline
  2. Review
  3. Review of a high-resourced cancer-related fatigue clinic and considerations in lower-resourced environments.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
    Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Rahul LadwaDivision of Cancer Services, Princess Alexandra Hospital, Brisbane, Queensland, Australia.
Elizabeth P PinkhamDivision of Cancer Services, Princess Alexandra Hospital, Brisbane, Queensland, Australia.
Laisa TeleniCentre for Healthcare Transformation, Queensland University of Technology, Brisbane, Queensland, Australia.
Brigid HanleyCancer Council Queensland, Brisbane, Queensland, Australia.
Gemma LockCancer Council Queensland, Brisbane, Queensland, Australia.
Jodie NixonOccupational Therapy Department, Princess Alexandra Hospital, Brisbane, Queensland, Australia.
Oluwaseyifunmi Andi AgbejuleCaring Futures Institute, Flinders University, Adelaide, South Australia, Australia.ORCID 0000-0003-2925-3362
Fiona Crawford-WilliamsCentre for Healthcare Transformation, Queensland University of Technology, Brisbane, Queensland, Australia.ORCID 0000-0002-3897-333X
Lee JonesCentre for Healthcare Transformation, Queensland University of Technology, Brisbane, Queensland, Australia.
Mark B PinkhamDivision of Cancer Services, Princess Alexandra Hospital, Brisbane, Queensland, Australia.
Jane TurnerSchool of Medicine, The University of Queensland, Brisbane, Queensland, Australia.
Patsy YatesDivision of Cancer Services, Princess Alexandra Hospital, Brisbane, Queensland, Australia.ORCID 0000-0001-8946-8504
Steven M McPhailCentre for Healthcare Transformation, Queensland University of Technology, Brisbane, Queensland, Australia.
Joanne F AitkenCancer Council Queensland, Brisbane, Queensland, Australia.
Carmen P EscalanteThe University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Nicolas H HartCentre for Healthcare Transformation, Queensland University of Technology, Brisbane, Queensland, Australia nicolas.hart@flinders.edu.au.ORCID 0000-0003-2794-0193
Raymond J ChanDivision of Cancer Services, Princess Alexandra Hospital, Brisbane, Queensland, Australia.ORCID 0000-0003-0248-7046

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionCancer-related fatigue (CRF) is one of the most common and debilitating adverse effects of cancer and its treatment reported by cancer survivors. Physical activity, psychological interventions and management of concurrent symptoms have been shown to be effective in alleviating CRF. This pilot randomised controlled trial (RCT) will determine the feasibility of a telehealth CRF clinic intervention (T-CRF) to implement evidence-based strategies and assess the impact of the intervention on CRF and other clinical factors in comparison to usual care. METHODS AND ANALYSIS: A parallel-arm (intervention vs usual care) pilot RCT will be conducted at the Princess Alexandra Hospital in Queensland, Australia. Sixty cancer survivors aged 18 years and over, who report moderate or severe fatigue on the Brief Fatigue Inventory and meet other study criteria will be recruited. Participants will be randomised (1:1) to receive the T-CRF intervention or usual care (ie, specialist-led care, with a fatigue information booklet). The intervention is a 24-week programme of three telehealth nurse-led consultations and a personalised CRF management plan. The primary objective of this pilot RCT is to determine intervention feasibility, with a secondary objective to determine preliminary clinical efficacy. Feasibility outcomes include the identification of recruitment methods; recruitment rate and uptake; attrition; adherence; fidelity; apathy; and intervention functionality, acceptability and satisfaction. Clinical and resource use outcomes include cancer survivor fatigue, symptom burden, level of physical activity, productivity loss, hospital resource utilisation and carer's fatigue and productivity loss. Descriptive statistics will be used to report on feasibility and process-related elements additional to clinical and resource outcomes. ETHICS AND DISSEMINATION: This trial is prospectively registered (ACTRN12620001334998). The study protocol has been approved by the Metro South Health and Hospital Services Human Research Ethics Committee (MSHHS HREC/2020/QMS/63495). Findings will be disseminated through peer-reviewed publications, national and international conferences and seminars or workshops. TRIAL REGISTRATION NUMBER: Australian New Zealand Clinical Trials Registry ID: ACTRN12620001334998; Pre-results. Trial Version: Version 1.1. Last updated 10 December 2020.

Indexed as

Cancer SurvivorsNeoplasmsTelemedicineAdolescentAdultAustraliaFatigueFeasibility StudiesHumansPilot ProjectsRandomized Controlled Trials as TopicCOMPLEMENTARY MEDICINEONCOLOGYTelemedicine

Identifiers

PMID35577469
PMCPMC9114967

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.