Evidence map›Paper›PMID 35576511›Full record

ArticleAnalytical chemistry2022

Lipid A Structural Determination from a Single Colony.

Hyojik Yang, Richard D Smith, Courtney E Chandler, J Kristie Johnson, Shelley N Jackson, Amina S Woods, Alison J Scott, David R Goodlett, Robert K Ernst

Open access · greenAbstract read
In one paragraph

Article in Analytical chemistry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
2.0field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 30 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. BECC-engineered live-attenuatedResearch square · 2024
    Article
  12. Article
  13. Article
  14. The multifaceted role of c-di-AMP signaling in the regulation ofFrontiers in cellular and infection microbiology · 2024
    Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 4 countries.

Hyojik YangDepartment of Microbial Pathogenesis, School of Dentistry, University of Maryland, Baltimore, Maryland 21201, United States.ORCID 0000-0002-1659-2771
Richard D SmithDepartment of Microbial Pathogenesis, School of Dentistry, University of Maryland, Baltimore, Maryland 21201, United States.
Courtney E ChandlerDepartment of Microbial Pathogenesis, School of Dentistry, University of Maryland, Baltimore, Maryland 21201, United States.
J Kristie JohnsonDepartment of Pathology, School of Medicine, University of Maryland, Baltimore, Maryland 21201, United States.
Shelley N JacksonTranslational Analytical Core, NIDA IRP, NIH, Biomedical Research Center, 251 Bayview Boulevard, Suite 200, Room 01B216, Baltimore, Maryland 21224, United States.
Amina S WoodsStructural Biology Core, NIDA IRP, NIH, 333 Cassell Drive, Room 1120, Baltimore, Maryland 21224, United States.ORCID 0000-0002-9716-345X
Alison J ScottDepartment of Microbial Pathogenesis, School of Dentistry, University of Maryland, Baltimore, Maryland 21201, United States.ORCID 0000-0001-6969-4707
David R GoodlettDepartment of Biochemistry and Microbiology, University of Victoria, 3800 Finnerty Road, Victoria, British Columbia V8P 5C2, Canada.
Robert K ErnstDepartment of Microbial Pathogenesis, School of Dentistry, University of Maryland, Baltimore, Maryland 21201, United States.
University of Maryland, Baltimore · USJohns Hopkins University · USNational Institute on Drug Abuse · USUniversity of Victoria · CA

Funding

Colistin-resistant Acinetobacter baumanniiR01AI104895 · NIAID · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI DOI, YOHEI, ERNST, ROBERT K · 2014 to 2024
$4.2M
MS Diagnostic Bacterial Identification LibraryR01AI147314 · NIAID · UNIVERSITY OF MARYLAND BALTIMORE · PI ERNST, ROBERT K, GOODLETT, DAVID ROBINSON · 2020 to 2024
$2.3M
MS diagnostic bacterial identification libraryR01GM111066 · NIGMS · UNIVERSITY OF MARYLAND BALTIMORE · PI ERNST, ROBERT K, GOODLETT, DAVID ROBINSON · 2014 to 2017
$1.2M
Intramural NIH HHS Z99 DA999999NIAID NIH HHS R01 AI104895NIAID NIH HHS R01 AI147314NIGMS NIH HHS R01 GM111066
6 · The paper itself

Abstract

We describe an innovative use for the recently reported fast lipid analysis technique (FLAT) that allows for the generation of MALDI tandem mass spectrometry data suitable for lipid A structure analysis directly from a single Gram-negative bacterial colony. We refer to this tandem MS version of FLAT as FLAT

Indexed as

Escherichia coli InfectionsEscherichia coli ProteinsAnti-Bacterial AgentsColistinDrug Resistance, BacterialEscherichia coliHumansLipid AMicrobial Sensitivity TestsAnti-Bacterial AgentsColistinEscherichia coli ProteinsLipid AMCR-1 protein, E coli

Identifiers

PMID35576511
PMCPMC9392460
OpenAlexW4280522196

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.